RT Journal A1 Selby JV, Beal AC, Frank L T1 THe patient-centered outcomes research institute (pcori) national priorities for research and initial research agenda JF JAMA JO JAMA YR 2012 FD April 18 VO 307 IS 15 SP 1583 OP 1584 DO 10.1001/jama.2012.500 UL http://dx.doi.org/10.1001/jama.2012.500 AB The Patient Protection and Affordable Care Act of 2010 created the Patient-Centered Outcomes Research Institute (PCORI) to fund and promote comparative clinical effectiveness research (CER) that will “assist patients, clinicians, purchasers, and policy-makers in making informed health decisions by advancing the quality and relevance of evidence concerning the manner in which diseases, disorders, and other health conditions can effectively and appropriately be prevented, diagnosed, treated, monitored, and managed through research and evidence synthesis.”1 CER is not a new concept,2- 3 but appreciation of its potential for providing patients and their clinicians with uniquely valuable information on what works, tailored to the clinical situation and to patient priorities, has increased rapidly in recent years.