RT Journal A1 Kuehn BM T1 CLinical trials website JF JAMA JO JAMA YR 2012 FD March 28 VO 307 IS 12 SP 1243 OP 1243 DO 10.1001/jama.2012.334 UL http://dx.doi.org/10.1001/jama.2012.334 AB NIH director Francis S. Collins, MD, PhD, explained in a statement that recruiting sufficient numbers of volunteers is a key challenge for clinical trials and that lack of information about what clinical trials are and how to participate may be keeping patients from enrolling.