RT Journal A1 Goldenberg AJ, Sharp RR T1 THe ethical hazards and programmatic challenges of genomic newborn screening JF JAMA JO JAMA YR 2012 FD February 1 VO 307 IS 5 SP 461 OP 462 DO 10.1001/jama.2012.68 UL http://dx.doi.org/10.1001/jama.2012.68 AB Advances in next-generation sequencing technologies have the potential to spur better integration of genetic testing into patient care. Appropriate utilization of these technologies will require the capacity to manage, interpret, and communicate large amounts of personal genetic information.1 Because the clinical infrastructure necessary to support these activities is currently limited,2 it is likely that the earliest applications of whole-genome sequencing will be restricted to settings in which genetic testing is already a routine part of clinical or public health practice, such as state newborn screening (NBS) programs.