RT Journal A1 Punnoose AR, Burke AE, Golub RM T1 CHildhood asthma JF JAMA JO JAMA YR 2012 FD January 25 VO 307 IS 4 SP 421 OP 421 DO 10.1001/jama.2011.2001 UL http://dx.doi.org/10.1001/jama.2011.2001 AB Asthma is one of the most common chronic illnesses in children. It occurs when small air passages in the lungs easily get inflamed and overreact to allergens and respiratory viral infections. When the muscles in the walls of the small air passages are stimulated by environmental allergens or infections, they release inflammatory agents that result in narrowing of the airways (bronchoconstriction ). This obstructs airflow and leads to the symptoms of asthma. The January 25, 2012, issue of JAMA includes an article on the treatment of children with asthma.