RT Journal A1 Miller DC, Hollenbeck BK T1 MIssing the mark on prostate-specific antigen screening JF JAMA JO JAMA YR 2011 FD December 28 VO 306 IS 24 SP 2719 OP 2720 DO 10.1001/jama.2011.1879 UL http://dx.doi.org/10.1001/jama.2011.1879 AB The US Preventive Services Task Force recently issued a draft recommendation against prostate-specific antigen (PSA) screening for prostate cancer.1 After performing a rigorous review of the relevant empirical literature, the task force concluded with “moderate certainty” that the harms of PSA-based detection (eg, biopsy-related complications) and early intervention (eg, incontinence, erectile dysfunction) exceed the potential benefits. For this reason, the task force now proposes discouraging PSA screening among men who are free of symptoms suspicious for prostate cancer.