RT Journal
A1 Torpy JM, Lynm C, Golub RM
T1 CArpal tunnel syndrome
JF JAMA
JO JAMA
YR 2011
FD November 23
VO 306
IS 20
SP 2283
OP 2283
DO 10.1001/jama.306.20.2283
UL http://dx.doi.org/10.1001/jama.306.20.2283
AB 
Carpal tunnel syndrome , a painful condition of the hands, affects millions of individuals around the world. Numbness, tingling, weakness, and pain are caused by compression and trapping of the median nerve. The median nerve  passes from the forearm into the hand underneath a band of connective tissue  (tough, fibrous material that connects the bones of the hand) that runs across the end of the forearm where the arm meets the hand. That triangular space, formed by bones and connective tissue, is called the carpal tunnel. The carpal tunnel contains not only the median nerve but also several tendons. Performing repeated tasks, such as with typing, computer work, or mechanical activity, puts individuals at risk of developing carpal tunnel syndrome. Weight gain, water retention, pregnancy, and overuse of the hands all can cause or worsen carpal tunnel syndrome.