RT Journal
A1 Hampton T
T1 BLocking cancer-induced epilepsy
JF JAMA
JO JAMA
YR 2011
FD November 2
VO 306
IS 17
SP 1853
OP 1853
DO 10.1001/jama.2011.1575
UL http://dx.doi.org/10.1001/jama.2011.1575
AB 
Immunodeficient mice implanted with human-derived glioma cells developed spontaneous and recurring abnormal brain activity; brain slices from these mice showed marked glutamate release from the tumor. When the researchers inhibited glutamate release from tumors with sulfasalazine at concentrations equivalent to those used to treat Crohn disease in humans, the mice had fewer epileptic events.