RT Journal A1 Chang HJ, Golub RM T1 INfluenza JF JAMA JO JAMA YR 2011 FD October 19 VO 306 IS 15 SP 1723 OP 1723 DO 10.1001/jama.306.15.1723 UL http://dx.doi.org/10.1001/jama.306.15.1723 AB Influenza (“flu”) is a contagious viral infection mainly affecting the nose, throat, airways, and lungs. It is one of the most changeable viruses; changes in the proteins of the virus can be small and continuous or abrupt. Flu outbreaks occur yearly, usually from November to March in the northern hemisphere. Approximately 5% to 20% of Americans are infected every flu season. Most people improve within a week, but for elderly people, infants and children, and people with some chronic diseases, influenza can be life-threatening. In the United States, more than 36 000 deaths and 200 000 hospitalizations are related to seasonal influenza each year. The October 19, 2011, issue of JAMA includes an article about H1N1 influenza. This Patient Page is based on one previously published in the November 4, 2009, issue of JAMA.