RT Journal
A1 Hampton T
T1 ANtiparasitic mucin
JF JAMA
JO JAMA
YR 2011
FD July 6
VO 306
IS 1
SP 30
OP 30
DO 10.1001/jama.2011.913
UL http://dx.doi.org/10.1001/jama.2011.913
AB 
The researchers previously found that the mice that were able to expel the whipworm Trichuris muris (which is closely related to the human equivalent, Trichuris trichiura) from the gut also made more mucus in the gut and that this mucus contained a sugar-coated protein, or mucin, called Muc5ac. In the new work, the team found that mice lacking the gene that encodes Muc5ac were incapable of expelling T muris from the intestine and harbored long-term infections despite mounting a strong immune response against the parasites.