RT Journal A1 Hampton T T1 ULcer insights JF JAMA JO JAMA YR 2012 FD January 4 VO 307 IS 1 SP 24 OP 24 DO 10.1001/jama.2011.1906 UL http://dx.doi.org/10.1001/jama.2011.1906 AB The researchers previously developed a strain of H pylori that is missing a gene essential for chemotaxis—the ability to sense and move in response to chemicals in the environment—and causes much less inflammation than normal strains. In this study, they found that immune responses to infections with the mutant strain lacked T-helper cell type 17 immune cells, which promote chronic inflammation in response to a combination of bacterial infection and dying host cells.