RT Journal A1 Sedlacek TV T1 COst-effectiveness of methods to enhance sensitivity of papanicolaou testing JF JAMA JO JAMA YR 1999 FD October 20 VO 282 IS 15 SP 1419 OP 1420 DO 10-1001/pubs.JAMA-ISSN-0098-7484-282-15-jac90009 UL http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-282-15-jac90009 AB The Eddy model on which this study was based was designed to study screening intervals, not cost-effectiveness. This flawed model was constructed on an old database, which does not reflect the impact of the human papillomavirus epidemic and did not screen patients younger than 35 years.2 Since cervical cancer has become such a rare disease, measuring changes in life-years saved is not relevant.