RT Journal A1 Weed DL T1 HIgher standards for epidemiologic studies—replication prior to publication? JF JAMA JO JAMA YR 1999 FD September 8 VO 282 IS 10 SP 937 OP 938 DO 10.1001/jama.282.10.937 UL http://dx.doi.org/10.1001/jama.282.10.937 AB To the Editor: In his commentary on epidemiologic studies and meta-analysis in drug development and surveillance, Dr Temple1 suggests that medical journals impose 3 higher standards on epidemiologic studies. Two of these should invoke little concern. Who is not in favor of any scientist doing a better job describing methods and their limitations? However, Temple's third suggestion—that epidemiologic studies with relative risks of 2.0 or less not be published until replicated in a different environment—is alarming.