RT Journal A1 Walter M, Berendes E, Claviez A, Suttorp M T1 INappropriate secretion of natriuretic peptides in a patient with a cerebral tumor JF JAMA JO JAMA YR 1999 FD July 7 VO 282 IS 1 SP 27 OP 28 DO 10-1001/pubs.JAMA-ISSN-0098-7484-282-1-jbk0707 UL http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-282-1-jbk0707 AB To the Editor: Increased plasma concentrations of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) may occur in myocardial infarction, renal insufficiency, and hypertension.1 The increased secretion of atrial natriuretic peptides from the heart is probably a physiologic reaction to volume overload but also may be due to other mechanisms. We describe a 10-month-old girl with a cerebral tumor and excessive diuresis and natriuresis, thus fulfilling the diagnosis of a cerebral salt-wasting syndrome, as described by Cort2 in the 1950s.