RT Journal A1 Bewtra C T1 AUtopsy rates and diagnosis JF JAMA JO JAMA YR 1999 FD June 16 VO 281 IS 23 SP 2181 OP 2181 DO 10-1001/pubs.JAMA-ISSN-0098-7484-281-23-jac90005 UL http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-281-23-jac90005 AB To the Editor: I completely agree with Dr Lundberg's1 suggestions to the Health Care Financing Administration and the Joint Commission on Accrediation of Healthcare Organizations for reviving the flagging autopsy rates in US hospitals. As a pathologist in a teaching hospital, I have watched our autopsy rate decrease drastically over the last 20 years. No amount of clinician education, pleas for teaching conferences, or decreased reporting time (currently 1 week for final report) has had any effect. I suggest that all national and regional cancer trial groups (Eastern Cooperative Oncology Group, North Central Cancer Treatment Group, etc) mandate autopsy of the enrolled patients as one of the requirements for participation in these trials. The extra cost should be included in the trial budget. At present, no such provision exists. Thus, we miss important knowledge regarding the effects of these new drugs and implements on cancer and healthy tissues.