RT Journal A1 Goyder E, Irwig L T1 SCreening for type 2 diabetes JF JAMA JO JAMA YR 1999 FD June 2 VO 281 IS 21 SP 1986 OP 1988 DO 10-1001/pubs.JAMA-ISSN-0098-7484-281-21-jbk0602 UL http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-281-21-jbk0602 AB First, the authors assume that screening merely brings forward the date of diagnosis. Their model and their estimate of the time between onset and clinical diagnosis are based on studies of clinically diagnosed cases. However, a population identified by screening would include many people whose condition would never be clinically apparent and who will die, mainly of cardiovascular disease (CVD), before clinical diagnosis and long before they would develop long-term microvascular complications. The model therefore may overestimate the risks of end-stage microvascular disease for screening-detected cases.