RT Journal
A1 Harari A, Iudica-Souza C
T1 GLycemic control and quality of life in patients with type 2 diabetes
JF JAMA
JO JAMA
YR 1999
FD June 2
VO 281
IS 21
SP 1985
OP 1986
DO 10-1001/pubs.JAMA-ISSN-0098-7484-281-21-jbk0602
UL http://dx.doi.org/10-1001/pubs.JAMA-ISSN-0098-7484-281-21-jbk0602
AB 
Of 1007 patients screened who went through placebo washout, only 594
were subsequently eligible for the study. Excluding this many patients
raises a question of selection bias and may not make the results of the
study applicable to the
general population.2 Additionally, 21%
of the patients had not been receiving any therapy prior to
randomization. Knowing how this population of untreated patients was
distributed in the 2 groups would be helpful.