RT Journal A1 Fuller DB T1 PRostatectomy, external beam radiation therapy, or brachytherapy for localized prostate cancer JF JAMA JO JAMA YR 1999 FD May 5 VO 281 IS 17 SP 1583 OP 1586 DO 10.1001/jama.281.17.1583 UL http://dx.doi.org/10.1001/jama.281.17.1583 AB First, intermediate- to high-risk patients, as defined in this study, had a 28% to 97% risk of having cancer cells beyond the prostate.2 As brachytherapy could undertreat cancer cells beyond the prostate, practitioners usually combine brachytherapy with external beam radiation in these cases. D'Amico et al give the potentially misleading impression that practitioners use brachytherapy alone against intermediate- to high-risk lesions, which does not reflect the standard practice for these patients.