RT Journal A1 Nordström C T1 CEll phone activation and brain glucose metabolism JF JAMA JO JAMA YR 2011 FD May 25 VO 305 IS 20 SP 2066 OP 2068 DO 10.1001/jama.2011.671 UL http://dx.doi.org/10.1001/jama.2011.671 AB To the Editor: The study by Dr Volkow and colleagues showed a relationship between brain glucose utilization rate and the amplitude of cell phone–emitted RF-EMFs.1 A high degree of correlation between absolute and normalized glucose metabolism and estimated RF-EMF amplitudes and increase in measures was demonstrated (Figure 3). However, these data are difficult to reconcile with the regional glucose metabolism in a representative participant (Figure 2). The increase in glucose metabolism in the orbitofrontal cortex in this participant was outside the cerebral areas exposed to the highest amplitude of RF-EMFs (Figure 1). Further, the temporal regions close to the emitting telephone did not exhibit a corresponding increase in glucose metabolism. It appears that cerebral areas quite far from the emitting source exhibited a more pronounced increase in glucose metabolism than that observed in the right temporal lobe.