RT Journal A1 Mitka M T1 TReatment for lupus, first in 50 years, offers modest benefits, hope to patients JF JAMA JO JAMA YR 2011 FD May 4 VO 305 IS 17 SP 1754 OP 1755 DO 10.1001/jama.2011.548 UL http://dx.doi.org/10.1001/jama.2011.548 AB Also, evidence regarding the efficacy of the new drug, belimumab (Benlysta, Human Genome Sciences), is largely confined to effects on the musculoskeletal and mucocutaneous systems. Patients with active lupus involving the kidney or central nervous system—2 sites often severely affected by the disease—were excluded from the 2 key trials examining benefits of the drug.