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RELATION BETWEEN GASTRIC AND RENAL DISEASES: Title and subTitle BreakCLINICAL OBSERVATIONS FREE

JULIUS FRIEDENWALD, M.D.; SAMUEL MORRISON, M.D.
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Read before the Section on Gastro-Enterology and Proctology at the Eighty-Third Annual Session of the American Medical Association, New Orleans, May 13, 1932.


BALTIMORE

From the Gastro-Enterological Clinic of the Department of Medicine, University of Maryland.


JAMA. 1932;99(7):524-529. doi:10.1001/jama.1932.02740590004002
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Gastro-intestinal symptoms occurring during the course of renal disease are not uncommon. These may be so pronounced that unless an extremely careful investigation is made, erroneous conclusions may easily be drawn, the primary condition remaining entirely unrecognized. This is more especially observed in the incipient stages of certain chronic renal diseases as well as in persons in the later periods of life, complaining of indigestion with urinary symptoms of a comparatively unimportant type, in whom the blood chemistry and functional renal tests reveal the presence of definite renal lesions.

On the other hand, attention has frequently been called to the fact that digestive diseases in themselves may likewise primarily produce disturbances of renal function.

The intimate relation between the kidneys and digestive organs will, to a great extent, easily account for many of these manifestations. Owing to beginning decompensation in the circulatory system, an early enlargement of the liver as

REFERENCES

Elwyn: Am. J. M. Sc. 179: 149, 1930;.
Auguste: Bull. et mém. Soc. méd. d. hôp. de Paris 53: 1313, 1929;.
Young, H. H.:  Use of Retained or Inlying Duodenal Tube in Treatment of Gastro-Intestinal Complications in Renal Disease , J. A. M. A. 94: 1830 ( (June 7) ) 1930;.
Van Valzah and Nisbet: The Diseases of the Stomach , Philadelphia, W. B. Saunders Company, 1898;, p. 639.
Biernaki: Berl. klin. Wchnschr. 28: 611 and 652, 1891;.
Jones: New York M. J. 61: 76, 1895;.
Zipkin: Inaug. Diss., Wurzburg, 1894.
Krakow: Inaug. Diss., St. Petersburg, 1891.
Brown, G. E.; Eusterman, G. B.; Hartman, H. R., and Rowntree, L. G.:  Toxic Nephritis in Pyloric and Duodenal Obstruction , Arch. Int. Med. 32: 425 ( (Sept.) ) 1923;.
Pfeiffer: Ann. Surg. 92: 900, 1930;.
Tileston, W., and Comfort, C. W., Jr.;  The Total Nonprotein Nitrogen and the Urea of the Blood in Health and in Disease as Estimated by Folin's Methods , Arch. Int. Med. 14: 620 ( (Nov.) ) 1914;.
Cooke, Rodenbaugh and Whipple: J. Exper. Med. 23: 717, 1916;.
McQuarrie and Whipple: J. Exper. Med. 29: 421, 1919;.
Hardt, L. L., and Rivers, A. B.:  Toxic Manifestations Following the Alkaline Treatment of Peptic Ulcer , Arch. Int. Med. 31: 171 ( (Feb.) ) 1923;.
Tucker: Wisconsin M. J. 20: 528, 1921;.
Zeman, Friedman and Mann: Proc. New York Path. Soc. 24: 41, 1924;.
Crohn: Affections of the Stomach , Philadelphia, W. B. Saunders Company, 1929;, p. 660.
Bennett: Nephritis: Its Problems and Treatment , New York, Oxford University Press, 1929;, p. 19.
Landau, Jochweds and Pekielis: Arch. d. mal. de l'app. digestif 18: 33, 1928;.
Redewill, F. H.; Potter, J. E., and Garrison, H. A.:  Colon as Site of Infection in Chronic Pyelitis, Cystitis and Prostatitis , J. A. M. A. 94: 688 ( (March 8) ) 1930;.

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Elwyn: Am. J. M. Sc. 179: 149, 1930;.
Auguste: Bull. et mém. Soc. méd. d. hôp. de Paris 53: 1313, 1929;.
Young, H. H.:  Use of Retained or Inlying Duodenal Tube in Treatment of Gastro-Intestinal Complications in Renal Disease , J. A. M. A. 94: 1830 ( (June 7) ) 1930;.
Van Valzah and Nisbet: The Diseases of the Stomach , Philadelphia, W. B. Saunders Company, 1898;, p. 639.
Biernaki: Berl. klin. Wchnschr. 28: 611 and 652, 1891;.
Jones: New York M. J. 61: 76, 1895;.
Zipkin: Inaug. Diss., Wurzburg, 1894.
Krakow: Inaug. Diss., St. Petersburg, 1891.
Brown, G. E.; Eusterman, G. B.; Hartman, H. R., and Rowntree, L. G.:  Toxic Nephritis in Pyloric and Duodenal Obstruction , Arch. Int. Med. 32: 425 ( (Sept.) ) 1923;.
Pfeiffer: Ann. Surg. 92: 900, 1930;.
Tileston, W., and Comfort, C. W., Jr.;  The Total Nonprotein Nitrogen and the Urea of the Blood in Health and in Disease as Estimated by Folin's Methods , Arch. Int. Med. 14: 620 ( (Nov.) ) 1914;.
Cooke, Rodenbaugh and Whipple: J. Exper. Med. 23: 717, 1916;.
McQuarrie and Whipple: J. Exper. Med. 29: 421, 1919;.
Hardt, L. L., and Rivers, A. B.:  Toxic Manifestations Following the Alkaline Treatment of Peptic Ulcer , Arch. Int. Med. 31: 171 ( (Feb.) ) 1923;.
Tucker: Wisconsin M. J. 20: 528, 1921;.
Zeman, Friedman and Mann: Proc. New York Path. Soc. 24: 41, 1924;.
Crohn: Affections of the Stomach , Philadelphia, W. B. Saunders Company, 1929;, p. 660.
Bennett: Nephritis: Its Problems and Treatment , New York, Oxford University Press, 1929;, p. 19.
Landau, Jochweds and Pekielis: Arch. d. mal. de l'app. digestif 18: 33, 1928;.
Redewill, F. H.; Potter, J. E., and Garrison, H. A.:  Colon as Site of Infection in Chronic Pyelitis, Cystitis and Prostatitis , J. A. M. A. 94: 688 ( (March 8) ) 1930;.
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