Professor of Bacteriology and Experimental Pathology, Stanford University School of Medicine; Instructor in Bacteriology, Stanford University School of Medicine; Associate (Elect) in General Physiology, Rockefeller Institute STANFORD UNIVERSITY, CALIF.
The experimental laboratory stands as the first buffer between suggested curative agents and their clinical application. A hundred instinctive "hunches" may be tested in order that three or four may be endorsed for clinical trial. Any therapeutic agent thus endorsed, however, now faces a second buffer, a mathematical law of clinical probability. For many suggested agents the mathematical probability for or against clinical success is readily calculated.
CALCULATED PROBABILITY WITH VACCINES AND ANTISERUMS Three decades of clinical experience with laboratory-endorsed vaccines and antiserums give ample data from which to calculate the probability coefficient for this class of therapeutic agents. Hundreds of theoretically logical, laboratory-endorsed vaccines and antiserums have been tried by clinicians; 95 per cent of them have been thrown into the clinical discard.An impartial mathematician would conclude from this that our fundamental immunologic theories and current experimental laboratory methods assay less than 5 per cent clinically verifiable truth.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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