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CLINICAL SIGNIFICANCE OF HUNGER PAINS: Title and subTitle BreakANALYSIS OF ONE HUNDRED AND SIXTY-TWO CASES OF GASTRO-INTESTINAL AND GALLBLADDER DISEASES FREE

WILLIAM H. HIGGINS, M.D.
[+] Author Affiliations

Read before the fifty-fourth annual meeting of the Medical Society of Virginia, Roanoke, Oct. 16, 1923.


JAMA. 1924;82(8):599-601. doi:10.1001/jama.1924.02650340009003
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The modern conception of gastric function constitutes a new chapter in physiology. On account of its accessibility, this organ has stimulated more experimental work and has attracted more general interest than probably any other part of the human anatomy. Within the span of a few years, radical changes have taken place. Ideas that were once accepted concerning it are now discarded, and many established facts of yesterday are crumbling in the light of our present knowledge.

HISTORICAL  One of these radical departures from former teachings is the modern interpretation of the hunger mechanism. For many years Haller's theory of the mechanical stimulation of sensory nerves in the gastric mucosa was generally accepted, and was the foundation of much of our therapeutics. Even Pawlow supported this idea and based his assumption on the effect of wine as a hunger excitant.Following this period, the view that the empty stomach was contracted

REFERENCES

Cannon, W. B., and Washburn, A. L.:  An Explanation of Hunger , Am. J. Physiol. 31: 309, 1911;.
Luckhardt, A. B., and Hamburger, W. W.:  Contributions to the Movements of the Empty Stomach, xxxiv, a Note on the Movements of the Empty Stomach in Certain Pathologic States , J. A. M. A. 66: 1831 ( (June 10) ) 1916;.
Spencer, Myer, Rehfuss and Hawk:  Direct Evidence of Duodenal Regurgitation and Its Influence Upon the Chemistry and Function of the Normal Stomach , Am. J. Physiol. 39: 459 ( (Feb.) ) 1916;.
Bassler: Diseases of the Digestive System 1: 600, 1922
Osler and McCrae: The Principles and Practice of Medicine , Ed. 9, 1920;, p. 485.
Moynihan: Duodenal Ulcer , Ed. 2, 1912;, p. 115.
Vaughan, W. T.:  Duodenal Ulcer and Cholecystitis , Virginia M. Month. 49: 34 ( (April) ) 1922;.
Carlson: The Control of Hunger in Health and Disease, 1916.

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Cannon, W. B., and Washburn, A. L.:  An Explanation of Hunger , Am. J. Physiol. 31: 309, 1911;.
Luckhardt, A. B., and Hamburger, W. W.:  Contributions to the Movements of the Empty Stomach, xxxiv, a Note on the Movements of the Empty Stomach in Certain Pathologic States , J. A. M. A. 66: 1831 ( (June 10) ) 1916;.
Spencer, Myer, Rehfuss and Hawk:  Direct Evidence of Duodenal Regurgitation and Its Influence Upon the Chemistry and Function of the Normal Stomach , Am. J. Physiol. 39: 459 ( (Feb.) ) 1916;.
Bassler: Diseases of the Digestive System 1: 600, 1922
Osler and McCrae: The Principles and Practice of Medicine , Ed. 9, 1920;, p. 485.
Moynihan: Duodenal Ulcer , Ed. 2, 1912;, p. 115.
Vaughan, W. T.:  Duodenal Ulcer and Cholecystitis , Virginia M. Month. 49: 34 ( (April) ) 1922;.
Carlson: The Control of Hunger in Health and Disease, 1916.
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