Authors are invited to submit manuscripts on any topic relevant to the biology, etiology, epidemiology, prevention, diagnosis, or treatment of oncologic disorders. A high priority will be given to rigorously conducted original research, especially multicenter randomized clinical trials that present new findings on treatment and novel therapeutic approaches for improving outcomes for common cancers. Careful consideration will be given to investigations exploring the genetic, genomic, and biomolecular aspects of cancer, as well as reports of basic science and translational investigations that provide novel insights about the biology, mechanisms, and pathophysiology of cancer. High-quality studies that present new data relevant to comparative effectiveness, improving prevention efforts, optimizing treatment strategies and health care delivery systems, and enhancing understanding of the functional, quality-of-life, and economic consequences of cancer care are also of interest.