To the Editor: Dr Stoll and colleagues1 confirm an association between adverse neurodevelopmental outcome and infection in extremely low-birth-weight (ELBW) infants. Of note is that there was a 30% increase in both neurodevelopmental impairment and poor head growth in infants with coagulase-negative staphylococcal sepsis and those with culture-negative clinical infection. These 2 groups represented about two thirds of all episodes of proven or suspected infection, so it is important that they are included in possible therapeutic trials of anti-inflammatory agents.2 We would like to know what proportion of culture-negative clinical infection was attributed to pneumonia. It would also be valuable to know whether necrotizing enterocolitis (NEC) alone (without prior, concurrent, or subsequently proven sepsis) was associated with adverse neurodevelopmental outcome.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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