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Association Between Thimerosal-Containing Vaccine and AutismAssociation Between Thimerosal-Containing Vaccine and Autism

JAMA. 2004;291(2):180-180. doi:10.1001/jama.291.2.180-a
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AUTHOR INFORMATION

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

ASSOCIATION BETWEEN THIMEROSAL-CONTAINING VACCINE AND AUTISM

To the Editor: In their article on the association between thimerosal-containing vaccines and autism, Dr Hviid and colleagues1 acknowledged their affiliations with Statens Serum Institut, Copenhagen, Denmark, but did not disclose that the institute is a for-profit, state-owned enterprise with roughly $120 million in annual revenue. According to its 2002 Annual Report,2 vaccines represent approximately one half of Statens Serum Institut's revenues and more than 80% of its profits. Furthermore, Statens Serum Institut manufactured the now discontinued monocomponent pertussis vaccine that contained thimerosal under investigation in their study. They were also the providers of diphtheria and tetanus components of a major thimerosal-containing diphtheria and tetanus toxoids and acellular pertussis vaccine (DTaP) vaccine sold in the United States.3

References
Hviid A, Stellfeld M, Wohlfahrt J, Melbye M. Association between thimerosal-containing vaccine and autism.  JAMA.2003;290:1763-1766.
PubMed
Statens Serum Institut.  2002 Annual ReportAvailable at: http://www.ssi.dk/sw3767.asp. Accessed October 12, 2003.
Food and Drug Administration.  Biologics license application approval letter to North American Vaccine. July 29, 1998. Available at: http://www.fda.gov/cber/approvltr/dtapnor072998L.htm. Accessed October 12, 2003.

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Hviid A, Stellfeld M, Wohlfahrt J, Melbye M. Association between thimerosal-containing vaccine and autism.  JAMA.2003;290:1763-1766.
PubMed
Statens Serum Institut.  2002 Annual ReportAvailable at: http://www.ssi.dk/sw3767.asp. Accessed October 12, 2003.
Food and Drug Administration.  Biologics license application approval letter to North American Vaccine. July 29, 1998. Available at: http://www.fda.gov/cber/approvltr/dtapnor072998L.htm. Accessed October 12, 2003.
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