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Dietary Risk Factors for Gastric CarcinomaDietary Risk Factors for Gastric Carcinoma

JAMA. 2004;291(13):1564-1564. doi:10.1001/jama.291.13.1564-a
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AUTHOR INFORMATION

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

DIETARY RISK FACTORS FOR GASTRIC CARCINOMA

To the Editor: In their Editorial about the relationship between Helicobacter pylori and gastric carcinoma, Drs Parsonnet and Forman1 did not discuss the dramatic decline in the use of salting and pickling food for preservation, which has mirrored the decline in US cases of gastric cancer during this period.2 Worldwide, there has been an ongoing reduction in salt intake.3 4 There is some evidence that the relevant carcinogens are produced from specific food items, such as those in fish, by salting and pickling, which involves the use of large amounts of salt and nitrates.5 Reducing salt intake may decrease the risk of gastric cancer, irrespective of the presence of H pylori.

References
Parsonnet J, Forman D. Helicobacter pylori infection and gastric cancer—for want of more outcomes.  JAMA.2004;291:244-245.
PubMed
Howson CP, Hiyama T, Wynder EL. The decline in gastric cancer: epidemiology of an unplanned triumph.  Epidemiol Rev.1986;8:1-27.
PubMed
Hirohata T, Kono S. Diet/nutrition and stomach cancer in Japan.  Int J Cancer.1997;Suppl 10:34-36.
PubMed
Correa P. Human gastric carcinogenesis: a multistep and multifactorial process—First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention.  Cancer Res.1992;52:6735-6740.
PubMed
Tsugane S, Sasazuki S, Kobayashi M, Sasaki S. Salt and salted food intake and subsequent risk of gastric cancer among middle-aged Japanese men and women.  Br J Cancer.2004;90:128-134.
PubMed

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Parsonnet J, Forman D. Helicobacter pylori infection and gastric cancer—for want of more outcomes.  JAMA.2004;291:244-245.
PubMed
Howson CP, Hiyama T, Wynder EL. The decline in gastric cancer: epidemiology of an unplanned triumph.  Epidemiol Rev.1986;8:1-27.
PubMed
Hirohata T, Kono S. Diet/nutrition and stomach cancer in Japan.  Int J Cancer.1997;Suppl 10:34-36.
PubMed
Correa P. Human gastric carcinogenesis: a multistep and multifactorial process—First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention.  Cancer Res.1992;52:6735-6740.
PubMed
Tsugane S, Sasazuki S, Kobayashi M, Sasaki S. Salt and salted food intake and subsequent risk of gastric cancer among middle-aged Japanese men and women.  Br J Cancer.2004;90:128-134.
PubMed
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