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Whole-Body Imaging for Cancer StagingWhole-Body Imaging for Cancer Staging

JAMA. 2004;291(11):1320-1320. doi:10.1001/jama.291.11.1320-b
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AUTHOR INFORMATION

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

WHOLE-BODY IMAGING FOR CANCER STAGING

To the Editor: Dr Antoch and colleagues1 reported that combined whole-body positron emission tomography and computed tomography (PET/CT) had greater diagnostic accuracy for cancer staging than did whole-body magnetic resonance imaging (MRI). I believe, however, that the authors' use of the term whole body is misleading, as their axial scanning range for both PET/CT and MRI did not appear to examine the brain, skull, or lower extremities. Lung cancer, for instance, commonly metastasizes to the brain. Furthermore, contrast-enhanced MRI has been reported to have higher sensitivity and specificity for brain metastases than PET.2 Although true whole-body PET requires additional time for image acquisition, it may provide a more accurate staging.

Financial Disclosure: Dr Osman has received honoraria from Petnet Pharmaceuticals and Shared Medical Services.

References
Antoch G, Vogt FM, Freudenberg LS.  et al.  Whole-body dual-modality PET/CT and whole-body MRI for tumor staging in oncology.  JAMA.2003;290:3199-3206.
PubMed
Rohern EM, Provenzale JM, Barboriak DP.  et al.  Screening for cerebral metastases with FDG PET in patients undergoing whole-body staging of non-central nervous system malignancy.  Radiology.2003;226:181-187.
PubMed

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Antoch G, Vogt FM, Freudenberg LS.  et al.  Whole-body dual-modality PET/CT and whole-body MRI for tumor staging in oncology.  JAMA.2003;290:3199-3206.
PubMed
Rohern EM, Provenzale JM, Barboriak DP.  et al.  Screening for cerebral metastases with FDG PET in patients undergoing whole-body staging of non-central nervous system malignancy.  Radiology.2003;226:181-187.
PubMed
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