Our bodies need fuel for proper function. Glucose (sugar) is the fuel that our cells use to produce energy. In order to process the sugar we eat in various foods, our bodies produce insulin. Insulin is a hormone made by beta cells, clusters of cells in the pancreas (an organ located in the upper abdomen). In type 1 diabetes, the beta cells in the pancreas are unable to make insulin because of autoimmune disease. This means that the body's immune system makes autoantibodies that attack and destroy the pancreatic beta cells. Type 2 diabetes is the result of the body's not being able to properly use the insulin made by the pancreas, and it occurs in adults and children who are overweight. Because type 1 diabetes usually starts in childhood, it is sometimes called juvenile diabetes. Type 1 diabetes is a serious illness that cannot be cured, but it can be treated and controlled. The October 22/29, 2003, issue of JAMA includes an article about type 1 diabetes.
Thirst
Frequent urination
Weight loss
Poor infant growth
High blood glucose level
Diabetic ketoacidosis—a life-threatening medical condition, also known as diabetic coma, is caused by the body's need to break down fats for energy instead of using sugars
Kidney failure
Diabetic retinopathy—damage to the retina of the eye
Gastroparesis—the stomach does not empty properly, allowing partially digested food to accumulate
Diabetic neuropathy—loss of sensation and nerve control of body functions
Increased occurrence of infections
Poor circulation, especially in the feet and legs
Coronary heart disease
Insulin injections—oral medications do not work
Diet
Exercise
Frequent checks of blood glucose levels
Management of other medical problems including high blood pressure and coronary heart disease
Screening for and early recognition of diabetes complications
Kidney dialysis or transplantation for kidney failure
Pancreas transplantation
Grahic Jump Location
National Institute of Diabetes & Digestive & Kidney Diseases 800/891-5390 http://www.niddk.nih.gov
American Diabetes Association 800/DIABETES (342-2383) http://www.diabetes.org
To find this and previous JAMA Patient Pages, go to the Patient Page link on JAMA's Web site at http://www.jama.com. Many are available in English and Spanish. A Patient Page on diabetes and the kidney was published in the June 25, 2003, issue; one on insulin was published in the May 7, 2003, issue; one on diabetes was published in the May 15, 2002, issue; one on type 2 diabetes in children was published in the September 26, 2001, issue; and one on managing type 2 diabetes was published in the January 12, 2000, issue.
Sources: National Institute of Diabetes & Digestive & Kidney Diseases; American Diabetes Association
The JAMA Patient Page is a public service of JAMA. The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis. For specific information concerning your personal medical condition, JAMA suggests that you consult your physician. This page may be photocopied noncommercially by physicians and other health care professionals to share with patients. Any other print or online reproduction is subject to AMA approval. To purchase bulk reprints, call 718/946-7424.
TOPIC: DIABETES
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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The Rational Clinical Examination Make the Diagnosis: Diabetes, Foot Ulcer
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