Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
To the Editor: In their Contempo Updates article about type 2 diabetes mellitus in children, Drs Ludwig and Ebbeling1 briefly discuss pharmacological agents and inaccurately state that "none have been approved for use in children by the Food and Drug Administration [FDA]."
In fact, after reviewing a supplemental application for use of metformin hydrochloride in children aged 10 to 16 years, the FDA concluded that this information demonstrated that the "drug product is safe and effective for use" in this age group. Final approval was granted on December 15, 2000. The package inserts have carried informational guidelines for use of this drug in children since January 2001. Other oral agents that have been used for management of type 2 diabetes in adults are currently undergoing clinical trials in children.
This article was corrected on February 13, 2002.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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