July 12, 2000July 12, 2000 FREE

Physicians with current and valid licenses in the United States, Canada, or Mexico who read any 3 of the selected continuing medical education (CME) articles in this issue of JAMA, complete the CME Evaluation Form, and fax it to the number or mail it to the address at the bottom of the CME Evaluation Form are eligible for category 1 CME credit. There is no charge.

The American Medical Association (AMA) is accredited by the Accreditation Council for Continuing Medical Education to sponsor CME for physicians. The AMA designates this educational activity for up to 1 hour of category 1 CME credit per JAMA issue toward the AMA Physician's Recognition Award (PRA). Each physician should claim for credit only those hours that were actually spent in this educational activity.

Physicians with current and valid licenses in the United States, Mexico, or Canada are eligible for CME credit even if they live or practice in other countries. Physicians licensed in other countries are also welcome to participate in this CME activity. However, the PRA is available only to physicians licensed in the United States, Canada, or Mexico.

To earn credit, read 3 of the articles listed below that are designated for CME credit carefully and complete the CME Evaluation Form. The CME Evaluation Form must be submitted within 1 month of the issue date. A certificate awarding 1 hour of category 1 CME credit will be faxed or mailed to you; it is then your responsibility to maintain a record of credit received.

One of our goals is to assess continually the educational needs of our readers so we may enhance the educational effectiveness of JAMA. To achieve this goal, we need your help. You must complete the CME Evaluation Form to receive credit.

JAMA is a general medical journal. Its mission and educational purpose is to promote the science and art of medicine and the betterment of the public health. A flexible curriculum of article topics is developed annually by THE JOURNAL's editorial board and is then supplemented throughout the year with information gained from readers, authors, reviewers, and editors. To accommodate the diversity of practice types within JAMA's readership, the Reader's Choice CME activity allows readers, as adult learners, to determine their own educational needs and to assist the editors in addressing their needs in future issues.

Readers of JAMA should be able to attain the following educational objectives: (1) select and read at least 3 articles in 1 issue to gain new medical information on topics of particular interest to them as physicians, (2) assess the articles' value to them as practicing physicians, and (3) think carefully about how this new information may influence their own practices. The educational objective for each CME article is given after the article title below.

The following articles in this issue may be read for CME credit:

Immunologic and Virologic Effects of Subcutaneous Interleukin 2 in Combination With Antiretroviral Therapy: A Randomized Controlled Trial Article

Educational Objective: To learn that supplementing antiretroviral therapy with interleukin 2 may further increase CD4 cell counts and decrease viral load.

Reduction in Mortality With Availability of Antiretroviral Therapy for Children With Perinatal HIV-1 Infection Article

Educational Objective: To learn that combined antiretroviral therapies may improve survival for HIV-infected children.

HIV Prevalence and Associated Risks in Young Men Who Have Sex With Men Article

Educational Objective: To learn that HIV infection remains common among young men who have sex with men.

Risk of Cancer in Children With AIDS Article

Educational Objective: To learn that several cancers may be associated with pediatric AIDS.

Failure of Routine HIV-1 Tests in a Case Involving Transmission With Preseroconversion Blood Components During the Infectious Window Period Article

Educational Objective: To learn that blood screening procedures using pooled sampler may not detect all HIV-contaminated blood products.

Current Evidence and Future Directions for Targeting HIV Entry: Therapeutic and Prophylactic Strategies Article

Educational Objective: To understand biological strategies for treatment and prevention of HIV infection.

Immune Restoration With Antiretroviral Therapies: Implications for Clinical Management Article

Educational Objective: To understand the benefits of immune restoration for patients with HIV infection.

Trends in Incidence and Prevalence of Major Transfusion-Transmissible Viral Infections in US Blood Donors Article

Educational Objective: To learn that behavioral screening of blood donors may have decreased the prevalence of transfusion-transmitted viral infections.

After reading 3 of these articles, complete the CME Evaluation Form.