0
ARTICLE |

Sickle Cell Trait and Sudden Death in Athletes FREE

Karen K. Kerle, MD; Guy P. Runkle, MD, MA
JAMA. 1996;276(18):1472-1472. doi:10.1001/jama.1996.03540180028023
Text Size: A A A
Published online

To the Editor.  —In their timely study on sudden death in athletes, Dr Maron and colleagues1 highlight hypertrophic cardiomyopathy as the major cause of sudden death in athletes younger than 35 years. However, we are concerned that the association between sudden death and sickle cell trait2 has not been adequately addressed in this article.The authors briefly mention 1 case of sudden death due to sickle cell trait. However, it is unclear how many of the 58 other black athletes in the series were sickle trait positive and how many were tested for the presence of hemoglobin AS. Because the association between sickle cell trait and sudden death is not widely appreciated, sickle cell trait may have been overlooked as an etiologic factor in the sudden death of several of these athletes.The prevalence of sickle cell trait is known to be 8% in the black population.3

REFERENCES

Maron BJ, Shirani J, Poliac LC, Mathenge R, Roberts WC, Mueller FO.  Sudden death in young competitive athletes: clinical, demographic, and pathological profiles . JAMA . 1996;;276:199-204.
Kerle KK, Nishimura KD.  Exertional collapse and sudden death associated with sickle cell trait . Am Fam Physician . 1996;;54:237-240.
Kark JA, Posey DM, Schumacher HR, Ruehle CJ.  Sickle cell trait as a risk factor for sudden death in physical training . N Engl J Med . 1987;;317:781-787.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Maron BJ, Shirani J, Poliac LC, Mathenge R, Roberts WC, Mueller FO.  Sudden death in young competitive athletes: clinical, demographic, and pathological profiles . JAMA . 1996;;276:199-204.
Kerle KK, Nishimura KD.  Exertional collapse and sudden death associated with sickle cell trait . Am Fam Physician . 1996;;54:237-240.
Kark JA, Posey DM, Schumacher HR, Ruehle CJ.  Sickle cell trait as a risk factor for sudden death in physical training . N Engl J Med . 1987;;317:781-787.
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.