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October 16, 1996, Vol 276, No. 15 >
ARTICLE | October 16, 1996

Epidemiologic Assessment of the Role of Blood Pressure in Stroke FREE

Niels A. Lassen, MD, PhD
[+] Author Affiliations

Corresponding author: Niels A. Lassen, MD, PhD, Department of Clinical Physiology and Nuclear Medicine, Bispebjerg Hospital, Bispebjerg, Bakke 23, DK-2400 Cophenhagen NV, Denmark.

A commentary on Kannel WB, Wolf PA, Verter J, McNamara PM. Epidemiologic assessment of the role of blood presure in stroke: the Framingham Study. JAMA. 1970;214:301-310.


JAMA. 1996;276(15):1279-1280. doi:10.1001/jama.1996.03540150081041
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IN 1970 William B. Kannel and his coworkers, Philip Wolf, Joel Verter, and Patricia McNamara, published in THE JOURNAL their important report from Framingham, Mass, on risk factors for stroke in a population followed prospectively for 14 years.1 At that time, hypertension, diabetes, and cigarette smoking had already been recognized as being the main risk factors, but the Framingham Study was among the first large-scale epidemiologic studies that followed a healthy adult population year after year, observed the diseases as they arose, and correlated them to a variety of possible risk factors.

The study was initiated in 1949 by Thomas R. Dawber from the National Heart Institute. It involved about 50% of adult residents aged 30 to 62 years, a total of 5209 subjects in the small township of Framingham. Its primary goal was to elucidate risks for heart disease, but soon stroke was given equal importance. The results

REFERENCES

1 +
Kannel WB, Wolf A, Verter J, McNamara PM.  Epidemiologic assessment of the role of blood pressure in stroke: the Framingham Study . JAMA . 1970;;214:301-310.
2 +
Veterans Administration Cooperative Study Group on Antihypertensive Agents.  Effects of treatment on morbidity in hypertension . JAMA . 1967;;202:116-122.
3 +
Menotti A, Jacobs DR, Blackburn H, et al.  Twenty-five year prediction of stroke deaths in the Seven Countries Study . Stroke . 1996;;27:381-387.
4 +
Collins R, MacMahon S.  Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease . Br Med Bull . 1994;;50;272-298.
5 +
Gorelick PB.  Stroke prevention . Stroke . 1994;;25:220-224.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Kannel WB, Wolf A, Verter J, McNamara PM.  Epidemiologic assessment of the role of blood pressure in stroke: the Framingham Study . JAMA . 1970;;214:301-310.
2 +
Veterans Administration Cooperative Study Group on Antihypertensive Agents.  Effects of treatment on morbidity in hypertension . JAMA . 1967;;202:116-122.
3 +
Menotti A, Jacobs DR, Blackburn H, et al.  Twenty-five year prediction of stroke deaths in the Seven Countries Study . Stroke . 1996;;27:381-387.
4 +
Collins R, MacMahon S.  Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease . Br Med Bull . 1994;;50;272-298.
5 +
Gorelick PB.  Stroke prevention . Stroke . 1994;;25:220-224.

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