Users' Guides to the Medical Literature: Title and subTitle BreakVII. How to Use a Clinical Decision Analysis B. What Are the Results and Will They Help Me in Caring for My Patients? FREE

W. Scott Richardson, MD; Allan S. Detsky, MD, PhD; Gordon Guyatt, MD, MSc; Deborah Cook, MD, MSc; Hertzel Gerstein, MD, MSc; Robert Hayward, MD, MPH; Anne Holbrook, MD, PharmD; Roman Jaeschke, MD, MSc; Elizabeth Juniper, MCSP, MSc; Mitchell Levine, MD, MSc; David Naylor, MD, DPhil; Andrew Oxman, MD, MSc; David Sackett, MD, MSc; Sean Tunis, MD, MSc; Stephen Walter, PhD; John Williams, Jr, MD, MHS; Mark Wilson, MD, MPH

[+] Author Affiliations

A complete list of members (with affiliations) of the Evidence-Based Medicine Working Group appears in the first article of this series (JAMA. 1993;270:2093-2095). The following members contributed to this article: Gordon Guyatt, MD, MSc (chair); Deborah Cook, MD, MSc; Hertzel Gerstein, MD, MSc; Robert Hayward, MD, MPH; Anne Holbrook, MD, PharmD; Roman Jaeschke, MD, MSc; Elizabeth Juniper, MCSP, MSc; Mitchell Levine, MD, MSc; David Naylor, MD, DPhil; Andrew Oxman, MD, MSc; David Sackett, MD, MSc; Sean Tunis, MD, MSc; Stephen Walter, PhD; John Williams, Jr, MD, MHS; and Mark Wilson, MD, MPH.

Reprint requests to Room 2C12, McMaster University Health Sciences Centre, 1200 Main St W, Hamilton, Ontario, Canada L8N 3Z5 (Gordon Guyatt, MD, MSc).

Users' Guides to the Medical Literature section editor: Drummond Rennie, MD, Deputy Editor (West), JAMA.

JAMA. 1995;273(20):1610-1613. doi:10.1001/jama.1995.03520440064038

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References

ABSTRACT

ABSTRACT | REFERENCES

YOU RECALL from the first of our two articles concerning clinical decision analysis¹ that your patient is a middle-aged man with heart failure from an idiopathic dilated cardiomyopathy. You are trying to decide whether to recommend anticoagulation with warfarin to prevent systemic or pulmonary thromboembolism. Your literature search showed that no randomized clinical trials of warfarin for this use have been published. The search did discover a clinical decision analysis,² and in the first article, we showed you how to evaluate its validity. In this article, we will show you how to interpret the results and generalizability of a clinical decision analysis (Table).

As shown in the Figure, decision trees are displayed graphically, oriented from left to right, with the decision to be analyzed on the left, the compared strategies in the center, and the clinical outcomes on the right. The square box, termed a "decision node," represents

REFERENCES

ABSTRACT | REFERENCES

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Guyatt GH, Sackett DL, Cook DJ, for the Evidence-Based Medicine Working Group. Users' guides to the medical literature, II: how to use an article about therapy or prevention, B: what were the results and will they help me in caring for my patients? JAMA . 1994;;271:59-63.

Jaeschke R, Guyatt GH, Sackett DL, for the Evidence-Based Medicine Working Group. Users' guides to the medical literature, III: how to use an article about a diagnostic test, A: are the results of the study valid? JAMA . 1994;;271:389-391.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal