0
ARTICLE |

The Accuracy of Drug Information From Pharmaceutical Sales Representatives FREE

Michael G. Ziegler, MD; Pauline Lew, PharmD; Brian C. Singer, PharmD
[+] Author Affiliations

Correspondence to UCSD Medical Center, 200 W Arbor Dr, San Diego, CA 92103-8341 (Dr Ziegler).


JAMA. 1995;273(16):1296-1298. doi:10.1001/jama.1995.03520400066047
Text Size: A A A
Published online

Objective.  —To provide quantitative data about the accuracy of the information about drugs presented to physicians by pharmaceutical sales representatives.

Design.  —One hundred six statements about drugs made during 13 presentations by pharmaceutical representatives were analyzed for accuracy. Statements were rated inaccurate if they contradicted the 1993 Physicians' Desk Reference or material quoted or handed out by the sales representative.

Setting.  —University teaching hospital.

Results.  —Twelve (11%) of 106 statements about drugs were inaccurate. All 12 inaccurate statements were favorable toward the promoted drug, whereas 39 (49%) of 79 accurate statements were favorable (P=.005). None of 15 statements about competitors' drugs were favorable, but all were accurate, significantly (P<.001) differing from statements about promoted drugs. In a survey of 27 physicians who attended these presentations, seven (26%) recalled any false statement made by a pharmaceutical representative, and 10 (37%) said information from the representatives influenced the way they prescribed drugs.

Conclusions.  —Eleven percent of the statements made by pharmaceutical representatives about drugs contradicted information readily available to them. Physicians generally failed to recognize the inaccurate statements.(JAMA. 1995;273:1296-1298)

REFERENCES

Lexchin J.  Doctors and detailers: therapeutic education or pharmaceutical promotion? Int J Health Serv . 1989;;19:663-679.
Avorn J, Chen M, Hartley R.  Scientific versus commercial sources of influence on the prescribing behavior of physicians. Am J Med . 1982;;73:4-8.
Lurie N, Rich EC, Simpson DE, et al.  Pharmaceutical representatives in academic medical centers: interaction with faculty and housestaff. J Gen Intern Med . 1990;;5:240-243.
McKinney WP, Schiedermayer DL, Lurie N, Simpson CE, Goodman JL, Rich EC.  Attitudes of internal medicine faculty and residents toward professional interaction with pharmaceutical sales representatives. JAMA . 1990;;264:1693-1697.
Margolis LH.  The ethics of accepting gifts from pharmaceutical companies. Pediatrics . 1991;;88:1233-1237.
Morris LA, Griffin JP.  The evolving role of FDA in prescription drug promotion. J Drug Issues . 1992;; 22:245-256.
Brotzman GL, Mark DH.  The effect on resident attitudes of regulatory policies regarding pharmaceutical representatives' activities. J Gen Intern Med . 1993;;8:130-134.
Lichstein PR, Turner RC, O'Brien K.  Impact of pharmaceutical company representatives on internal medicine residency programs. Arch Intern Med . 1992;;152:1009-1013.
Skolnick AA.  Pro-free enterprise group challenges FDA's authority to regulate drug companies' speech. JAMA . 1994;;271:332-335.
Hemminki E.  Content analysis of drug-detailing by pharmaceutical representatives. Med Educ . 1977;;11:210-215.
Parsons LJ, Abeele PV.  Analysis of sales call effectiveness. J Marketing Res . 1981;;18:107-113.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Lexchin J.  Doctors and detailers: therapeutic education or pharmaceutical promotion? Int J Health Serv . 1989;;19:663-679.
Avorn J, Chen M, Hartley R.  Scientific versus commercial sources of influence on the prescribing behavior of physicians. Am J Med . 1982;;73:4-8.
Lurie N, Rich EC, Simpson DE, et al.  Pharmaceutical representatives in academic medical centers: interaction with faculty and housestaff. J Gen Intern Med . 1990;;5:240-243.
McKinney WP, Schiedermayer DL, Lurie N, Simpson CE, Goodman JL, Rich EC.  Attitudes of internal medicine faculty and residents toward professional interaction with pharmaceutical sales representatives. JAMA . 1990;;264:1693-1697.
Margolis LH.  The ethics of accepting gifts from pharmaceutical companies. Pediatrics . 1991;;88:1233-1237.
Morris LA, Griffin JP.  The evolving role of FDA in prescription drug promotion. J Drug Issues . 1992;; 22:245-256.
Brotzman GL, Mark DH.  The effect on resident attitudes of regulatory policies regarding pharmaceutical representatives' activities. J Gen Intern Med . 1993;;8:130-134.
Lichstein PR, Turner RC, O'Brien K.  Impact of pharmaceutical company representatives on internal medicine residency programs. Arch Intern Med . 1992;;152:1009-1013.
Skolnick AA.  Pro-free enterprise group challenges FDA's authority to regulate drug companies' speech. JAMA . 1994;;271:332-335.
Hemminki E.  Content analysis of drug-detailing by pharmaceutical representatives. Med Educ . 1977;;11:210-215.
Parsons LJ, Abeele PV.  Analysis of sales call effectiveness. J Marketing Res . 1981;;18:107-113.
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.