0
ARTICLE |

Comparability of Capillary and Venous Blood Samples for Lead Screening FREE

Petrie M. Rainey, MD, PhD; David J. Schonfeld, MD
JAMA. 1994;272(19):1482-1482. doi:10.1001/jama.1994.03520190024016
Text Size: A A A
Published online

To the Editor.  —To achieve the goal of blood lead screening for all children aged 6 months to 6 years,1 testing should be easy to perform, widely available, inexpensive, and reliable. Specimens are more easily obtained from children by fingerstick than by venipuncture. However, increased opportunity for contamination of capillary specimens has raised concerns about their reliability. Dr Schlenker and colleagues2 compared capillary and venous blood lead levels in children and showed that between 0% and 5% (depending on sampling protocol) of the capillary results were false positives and 1% to 8% false negatives.2These percentages were referred to as false-positive and false-negative rates, which may lead to confusion. For example, the term "false-positive rate" traditionally has meant the percentage of false positives in the total positives (false positives/[false positives + true positives]).3 Only this statistic has predictive value for determining the significance of a positive test.

REFERENCES

Centers for Disease Control. Preventing Lead Poisoning in Young Children . Atlanta, Ga: Centers for Disease Control; October 1991;.
Schlenker TL, Fritz CJ, Mark D, et al.  Screening for pediatric lead poisoning: comparability of simultaneously drawn capillary and venous blood samples. JAMA . 1994;;271:1346-1348.
Feinstein AR. Clinical Biostatistics . St Louis, Mo: CV Mosby; 1977;.
Schonfeld DS, Cullen MR, Rainey PM, et al.  Screening for lead poisoning in an urban pediatric clinic using samples obtained by fingerstick. Pediatrics . In press.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Centers for Disease Control. Preventing Lead Poisoning in Young Children . Atlanta, Ga: Centers for Disease Control; October 1991;.
Schlenker TL, Fritz CJ, Mark D, et al.  Screening for pediatric lead poisoning: comparability of simultaneously drawn capillary and venous blood samples. JAMA . 1994;;271:1346-1348.
Feinstein AR. Clinical Biostatistics . St Louis, Mo: CV Mosby; 1977;.
Schonfeld DS, Cullen MR, Rainey PM, et al.  Screening for lead poisoning in an urban pediatric clinic using samples obtained by fingerstick. Pediatrics . In press.
CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.