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ARTICLE |

Measles Immunization of 2-Year-Olds in a Rural Southern State FREE

Sandor Feldman, MD; Michael Andrew, PhD; John Gilbert, MA, ELS; Bruce Bracken, MPH; F. Edgar Thompson, MD, MPH
[+] Author Affiliations

Reprint requests to Department of Pediatrics, University of Mississippi Medical Center, 2500 N State St, Jackson, MS 39216 (Dr Feldman).


JAMA. 1994;271(18):1417-1420. doi:10.1001/jama.1994.03510420049033
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Objective.  —To assess the measles vaccine coverage of 2-year-old children living in Mississippi during the national measles epidemic of 1989 and 1990.

Design.  —Survey of 2-year-olds randomly selected from the 1987 birth cohort. The status of measles-mumps-rubella (MMR) vaccination was determined by medical record reviews and family contacts.

Setting.  —A predominantly rural state in the southeastern United States with a large black minority population (35%) and a low per capita income ($9827 to $12899). Approximately 80% of MMR immunizations are given by public health service nurses working in nine health districts.

Subjects.  —A total of 2450 preschool-aged children representing 6% of the 1987 birth cohort (n=41 279). Three hundred forty-one children were considered ineligible, leaving 2109 in the final sample.

Main Outcome Measures.  —Confirmed vaccination by the age of 2 years. Rates of immunization were calculated for the entire state, its health districts, and subgroups based on population density, per capita income, type of clinic visited, and race.

Results.  —The statewide immunization rate was 87% (95% confidence interval, 86% to 88%). Among the nine health districts, rates varied from 79% to 97% (median, 88%). They were similar for white and black children in each health district and within the state as a whole. The level of vaccine coverage was significantly higher in districts with lower population densities (89% vs 85%, P=.02) and in those with higher per capita incomes (89% vs 86%, P=.03). There were four minor outbreaks of measles during 1989 and 1990; half of the cases occurred in unimmunized children too young to receive the MMR vaccine.

Conclusion.  —A high rate of measles immunization is attainable among 2-year-olds living in a rural state with a large black minority population and limited economic resources.(JAMA. 1994;271:1417-1420)

REFERENCES

Gindler JS, Atkinson WL, Markowitz LE, Hutchins SS.  Epidemiology of measles in the United States in 1989 and 1990. Pediatr Infect Dis J . 1992;;11:841-846.
Schlenker TL, Bain C, Baughman AL, Hadler SC.  Measles herd immunity: the association of attack rates with immunization rates in preschool children. JAMA . 1992;;267:823-826.
Katz S.  The politics of measles. Rep Pediatr Infect Dis . 1991;;1:1-2.
The National Vaccine Advisory Committee.  The measles epidemic: the problems, barriers, and recommendations. JAMA . 1991;;266:1547-1552.
Centers for Disease Control.  Measles vaccination levels among selected groups of preschool-age children—US. MMWR Morb Mortal Wkly Rep . 1991;;40:36-39.
Statistical Abstract of the United States . 112th ed. Washington, DC: US Dept of Commerce; 1992;: 22-23.
Report of the Bureau of Economic Analysis . Jackson: Mississippi Employment Security Commission; 1992;:8-10.
Vital Statistics, Mississippi, 1991 . Jackson: Mississippi State Dept of Health; 1992;:43-45.
Daniel WW. Biostatistics in the Health Sciences: A Foundation for Analysis . 4th ed. New York, NY: John Wiley & Sons Inc; 1987;:155-156.
Guenther W. Concepts of Statistical Inference . 2nd ed. New York, NY: McGraw-Hill; 1973;:517-519.
Cutts FT, Zell ER, Mason D, Bernier RH, Dini EF, Orenstein WA.  Monitoring progress toward US preschool immunization goals. JAMA . 1992;;267: 1952-1955.
Farizo KM, Stehr-Green PA, Markowitz LE, Patriarca PA.  Vaccination levels and missed opportunities for measles vaccination: a record audit in a public pediatric clinic. Pediatrics . 1992;;89:589-592.
Freed GL, Katz SL.  The Comprehensive Childhood Immunization Act of 1993: toward a more rational approach. N Engl J Med . 1993;;329:1957-1960.
Centers for Disease Control and Prevention.  Vaccination coverage of 2-year-old children—United States, 1991-1992. MMWR Morb Mortal Wkly Rep . 1994;;42:985-988.
National Education Association. Rankings of the States, 1991 . Washington, DC: National Education Association; 1991;:54-61.
Langbein LI, Lichtman AJ. Ecological Inference . Beverly Hills, Calif: Sage Publications Inc; 1978;:9-11.
Wojciechowski B, Darden PM, Ector WL.  Do postcard prompts increase immunizations in children? Clin Res . 1992;;40:809A.
Young SA, Halpin TJ, Johnson DA, Irvin JJ, Marks JS.  Effectiveness of a mailed reminder on the immunization levels of infants at high risk of failure to complete immunizations. Am J Public Health . 1980;;70:422-424.
Public Health Practice Program Office. State Health Agency Organization Charts . Washington, DC: Public Health Foundation; 1992;.
Centers for Disease Control.  Measles—United States, 1990. MMWR Morb Mortal Wkly Rep . 1991;; 40:369-372.
Fox JP, Elveback L, Scott W, Gatewood L, Ackerman E.  Herd immunity: basic concept and relevance to public health immunization practices. Am J Epidemiol . 1971;;94:179-189.
Jones VF, Badgett JT, Minella JL.  Immunization profile: a birth certificate based survey. Clin Res . 1992;;40:809A.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Gindler JS, Atkinson WL, Markowitz LE, Hutchins SS.  Epidemiology of measles in the United States in 1989 and 1990. Pediatr Infect Dis J . 1992;;11:841-846.
Schlenker TL, Bain C, Baughman AL, Hadler SC.  Measles herd immunity: the association of attack rates with immunization rates in preschool children. JAMA . 1992;;267:823-826.
Katz S.  The politics of measles. Rep Pediatr Infect Dis . 1991;;1:1-2.
The National Vaccine Advisory Committee.  The measles epidemic: the problems, barriers, and recommendations. JAMA . 1991;;266:1547-1552.
Centers for Disease Control.  Measles vaccination levels among selected groups of preschool-age children—US. MMWR Morb Mortal Wkly Rep . 1991;;40:36-39.
Statistical Abstract of the United States . 112th ed. Washington, DC: US Dept of Commerce; 1992;: 22-23.
Report of the Bureau of Economic Analysis . Jackson: Mississippi Employment Security Commission; 1992;:8-10.
Vital Statistics, Mississippi, 1991 . Jackson: Mississippi State Dept of Health; 1992;:43-45.
Daniel WW. Biostatistics in the Health Sciences: A Foundation for Analysis . 4th ed. New York, NY: John Wiley & Sons Inc; 1987;:155-156.
Guenther W. Concepts of Statistical Inference . 2nd ed. New York, NY: McGraw-Hill; 1973;:517-519.
Cutts FT, Zell ER, Mason D, Bernier RH, Dini EF, Orenstein WA.  Monitoring progress toward US preschool immunization goals. JAMA . 1992;;267: 1952-1955.
Farizo KM, Stehr-Green PA, Markowitz LE, Patriarca PA.  Vaccination levels and missed opportunities for measles vaccination: a record audit in a public pediatric clinic. Pediatrics . 1992;;89:589-592.
Freed GL, Katz SL.  The Comprehensive Childhood Immunization Act of 1993: toward a more rational approach. N Engl J Med . 1993;;329:1957-1960.
Centers for Disease Control and Prevention.  Vaccination coverage of 2-year-old children—United States, 1991-1992. MMWR Morb Mortal Wkly Rep . 1994;;42:985-988.
National Education Association. Rankings of the States, 1991 . Washington, DC: National Education Association; 1991;:54-61.
Langbein LI, Lichtman AJ. Ecological Inference . Beverly Hills, Calif: Sage Publications Inc; 1978;:9-11.
Wojciechowski B, Darden PM, Ector WL.  Do postcard prompts increase immunizations in children? Clin Res . 1992;;40:809A.
Young SA, Halpin TJ, Johnson DA, Irvin JJ, Marks JS.  Effectiveness of a mailed reminder on the immunization levels of infants at high risk of failure to complete immunizations. Am J Public Health . 1980;;70:422-424.
Public Health Practice Program Office. State Health Agency Organization Charts . Washington, DC: Public Health Foundation; 1992;.
Centers for Disease Control.  Measles—United States, 1990. MMWR Morb Mortal Wkly Rep . 1991;; 40:369-372.
Fox JP, Elveback L, Scott W, Gatewood L, Ackerman E.  Herd immunity: basic concept and relevance to public health immunization practices. Am J Epidemiol . 1971;;94:179-189.
Jones VF, Badgett JT, Minella JL.  Immunization profile: a birth certificate based survey. Clin Res . 1992;;40:809A.
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