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July 14, 1993, Vol 270, No. 2 >
ARTICLE | July 14, 1993

Transplantation FREE

Mark A. Hardy, MD; Elliot R. Goodman, MD
JAMA. 1993;270(2):262-265. doi:10.1001/jama.1993.03510020130047
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References

Many advances in clinical and experimental transplantation have occurred in recent years. Significant progress has been made to solve the universal problems of donor organ shortages and the dependency of recipients on chronic immunosuppression. Pioneering efforts in small-bowel and islet cell transplantation are of particular interest because of their potential impact on patient care and the field of transplantation.

Donor shortages lengthen waiting lists for all organs worldwide. The waiting time for a cadaveric renal transplant may be over 500 days.1 The mortality rate for children with end-stage chronic liver disease who are awaiting transplantation is nearly 25%.2 There are several means currently used to shorten waiting lists, with others currently under experimental consideration. First of all, living unrelated donors may be used for kidney transplantation. It is accepted that living unrelated renal transplantation (LURTx) is ethically permissible if no suitable kidney transplant is available from a cadaveric

REFERENCES

1 +
Sollinger HW.  Invited commentary on 'Living unrelated donor kidney transplantation between spouses.' World J Surg . 1992;;16: 1187.
2 +
Brolsch CE, Stevens LH, Whitington PF, et al.  The use of reduced-size liver transplants in children, including split livers and living related liver transplants. Eur J Pediatr Surg . 1991;;1:166-177.
3 +
Haberal M, Gulay H, Tokyay R, et al.  Living unrelated donor kidney transplantation between spouses. World J Surg . 1992;;16: 1183-1187.
4 +
Pirsch JD, D'Alessandro AM, Sollinger HW, et al.  Living unrelated renal transplantation.  In: Terasaki PI, ed. Clinical Transplants 1990 . Los Angeles, Calif: UCLA; 1990;:241-245.
5 +
Kaiser LR, Cooper JD, Trulock EP, et al.  The evolution of single lung transplantation for emphysema. J Thorac Cardiovasc Surg . 1991;;102:333-339.
6 +
Pasque MK, Kaiser LR, Dresler CM, et al.  Single lung transplantation for pulmonary hypertension: technical aspects and immediate hemodynamic results. J Thorac Cardiovasc Surg . 1992;; 103:475-481.
7 +
Starnes VA, Oyer PE, Bernstein D, et al.  Heart, heart-lung and lung transplantation in the first year of life. Ann Thorac Surg . 1992;;53:306-310.
8 +
Low DE, Trulock EP, Kaiser LR, et al.  Morbidity, mortality and early results of single versus bilateral lung transplantation. J Thorac Cardiovasc Surg . 1992;;103:1119-1126.
9 +
Starzl TE.  Liver allo-and xenotransplantation. Transplant Proc . 1993;;25:15-17.
10 +
Platt JL.  Mechanisms of tissue injury in hyperacute xenograft rejection. ASAIO J . 1992;;38:8-16.
11 +
Fischel RJ, Platt JL, Matas AJ, et al.  Prolonged survival of a discordant cardiac xenograft in a rhesus monkey. Transplant Proc . 1991;;23:589-590.
12 +
White DJG, Yannoutsos N, Cary N, et al. The genetic control of complement activation inhibits hyperacute rejection of discordant xenografts. In: Proceedings of the XIVth International Congress of the Transplantation Society; August 17, 1992; Paris, France. Abstract 29.
13 +
Starzl TE, Trucco M, Zeevi A, et al.  Systemic chimerism in human female recipients of male livers. Lancet . 1992;;340:876-877.
14 +
Starzl TE, Murase N, Demetris AJ, et al.  Drug development and testing in relation to cell migration and chimerism. Transplant Proc . 1993;;25:469-472.
15 +
Todo S, Tzakis AG, Abu-Elmagd K, et al.  Intestinal transplantation in composite visceral grafts or alone. Ann Surg . 1992;;216: 223-233.
16 +
Goulet O, Revillon Y, Brousse N, et al.  Successful small bowel transplantation in an infant. Transplantation . 1992;;53:940-943.
17 +
Najarian JS, Sutherland DE.  Pancreas transplantation 1991. Transplant Proc . 1992;;24:1293-1296.
18 +
Ricordi C, Tzakis AG, Carroll PB, et al.  Human islet isolation and allotransplantation in 22 consecutive cases. Transplantation . 1992;;53:407-414.
19 +
Carroll PB, Ricordi C, Shapiro R, et al. Frequency of kidney rejection in diabetic patients undergoing simultaneous kidney and pancreatic islet cell transplantation. In: Abstracts from the meeting of the American Society of Transplant Surgeons; May 1992; Chicago, Ill:67.
20 +
Nussler AK, Carroll PB, Di Silvio M, et al.  Hepatic nitric oxide generation as a putative mechanism for failure of intrahepatic islet cell grafts. Transplant Proc . 1992;;24:2997.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

1 +
Sollinger HW.  Invited commentary on 'Living unrelated donor kidney transplantation between spouses.' World J Surg . 1992;;16: 1187.
2 +
Brolsch CE, Stevens LH, Whitington PF, et al.  The use of reduced-size liver transplants in children, including split livers and living related liver transplants. Eur J Pediatr Surg . 1991;;1:166-177.
3 +
Haberal M, Gulay H, Tokyay R, et al.  Living unrelated donor kidney transplantation between spouses. World J Surg . 1992;;16: 1183-1187.
4 +
Pirsch JD, D'Alessandro AM, Sollinger HW, et al.  Living unrelated renal transplantation.  In: Terasaki PI, ed. Clinical Transplants 1990 . Los Angeles, Calif: UCLA; 1990;:241-245.
5 +
Kaiser LR, Cooper JD, Trulock EP, et al.  The evolution of single lung transplantation for emphysema. J Thorac Cardiovasc Surg . 1991;;102:333-339.
6 +
Pasque MK, Kaiser LR, Dresler CM, et al.  Single lung transplantation for pulmonary hypertension: technical aspects and immediate hemodynamic results. J Thorac Cardiovasc Surg . 1992;; 103:475-481.
7 +
Starnes VA, Oyer PE, Bernstein D, et al.  Heart, heart-lung and lung transplantation in the first year of life. Ann Thorac Surg . 1992;;53:306-310.
8 +
Low DE, Trulock EP, Kaiser LR, et al.  Morbidity, mortality and early results of single versus bilateral lung transplantation. J Thorac Cardiovasc Surg . 1992;;103:1119-1126.
9 +
Starzl TE.  Liver allo-and xenotransplantation. Transplant Proc . 1993;;25:15-17.
10 +
Platt JL.  Mechanisms of tissue injury in hyperacute xenograft rejection. ASAIO J . 1992;;38:8-16.
11 +
Fischel RJ, Platt JL, Matas AJ, et al.  Prolonged survival of a discordant cardiac xenograft in a rhesus monkey. Transplant Proc . 1991;;23:589-590.
12 +
White DJG, Yannoutsos N, Cary N, et al. The genetic control of complement activation inhibits hyperacute rejection of discordant xenografts. In: Proceedings of the XIVth International Congress of the Transplantation Society; August 17, 1992; Paris, France. Abstract 29.
13 +
Starzl TE, Trucco M, Zeevi A, et al.  Systemic chimerism in human female recipients of male livers. Lancet . 1992;;340:876-877.
14 +
Starzl TE, Murase N, Demetris AJ, et al.  Drug development and testing in relation to cell migration and chimerism. Transplant Proc . 1993;;25:469-472.
15 +
Todo S, Tzakis AG, Abu-Elmagd K, et al.  Intestinal transplantation in composite visceral grafts or alone. Ann Surg . 1992;;216: 223-233.
16 +
Goulet O, Revillon Y, Brousse N, et al.  Successful small bowel transplantation in an infant. Transplantation . 1992;;53:940-943.
17 +
Najarian JS, Sutherland DE.  Pancreas transplantation 1991. Transplant Proc . 1992;;24:1293-1296.
18 +
Ricordi C, Tzakis AG, Carroll PB, et al.  Human islet isolation and allotransplantation in 22 consecutive cases. Transplantation . 1992;;53:407-414.
19 +
Carroll PB, Ricordi C, Shapiro R, et al. Frequency of kidney rejection in diabetic patients undergoing simultaneous kidney and pancreatic islet cell transplantation. In: Abstracts from the meeting of the American Society of Transplant Surgeons; May 1992; Chicago, Ill:67.
20 +
Nussler AK, Carroll PB, Di Silvio M, et al.  Hepatic nitric oxide generation as a putative mechanism for failure of intrahepatic islet cell grafts. Transplant Proc . 1992;;24:2997.

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