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ARTICLE |

Long-term Outcome of Critically III Elderly Patients Requiring Intensive Care FREE

Lakshmipathi Chelluri, MD; Michael R. Pinsky, MD; Michael P. Donahoe, MD; Ake Grenvik, MD
[+] Author Affiliations

Reprint requests to Scaife Hall, Room 608, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 (Dr Chelluri).


JAMA. 1993;269(24):3119-3123. doi:10.1001/jama.1993.03500240063027
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Objective.  —To evaluate the long-term mortality and morbidity of critically ill elderly patients requiring intensive care.

Design.  —Prospective comparison of outcome of critically ill patients aged 75 years and older with patients aged 65 to 74 years.

Patients.  —Critically ill patients aged 65 years and older who required intensive care and who were recruited during a 3-month period.

Main Outcome Measures.  —Duration of hospitalization, hospital charges, procedures used in the intensive care unit, mortality in the hospital and during the follow-up period, and quality of life of survivors during the follow-up period.

Results.  —Ninety-seven patients were included in the study; 54 were 75 years or older and 43 were aged 65 to 74 years. No significant difference was noted between the two groups for length of stay in the hospital, hospital charges, or mortality at 1 year. Severity of illness, as assessed by Acute Physiology and Chronic Health Evaluation score at the time of intensive care unit admission, was a better predictor of survival than age. Quality of life, as assessed by activities of daily living, perceived quality of life, and Center for Epidemiologic Studies—Depression score, were not significantly different in either group at 1, 6, and 12 months after discharge from the hospital. Most patients in both groups described their quality of life as adequate and were willing to receive intensive care again, if necessary.

Conclusion.  —Age alone is not an adequate predictor of long-term survival and quality of life in critically ill elderly patients.(JAMA. 1993;269:3119-3123)

REFERENCES

Martin L.  Population aging policies in East Asia and the United States. Science . 1991;;251:527-532.
Rowe JW, Grossman E, Bond E.  Academic geriatrics for the year 2000: an institute of medicine report. N Engl J Med . 1987;;316:1425-1428.
Le Gall JR, Brun-Buisson C, Trunet P, Latournerie J, Chantereau S, Rapin M.  Influence of age, previous health status, and severity of acute illness on outcome from intensive care. Crit Care Med . 1982;;10:575-577.
Campion EW, Mulley AG, Goldstein RL, Barnett GO, Thibault E.  Medical intensive care for the elderly. JAMA . 1981;;246:2052-2056.
Cullen DJ, Keene R, Waternaux C, Kunsman JM, Caldera DL, Peterson H.  Results, charges and benefits of intensive care for critically ill patients: update 1983. Crit Care Med . 1984;;12:102-106.
Potgieter PD, Rosenthal E, Benatar SR.  Immediate and long-term survival in patients admitted to a respiratory ICU. Crit Care Med . 1985;;13:798-802.
McClish DK, Powell SH, Montenegro H, Nochomovitz M.  The impact of age on utilization of intensive care resources. J Am Geriatr Soc . 1987;;35: 983-988.
Mayer-Oakes SA, Oye RK, Leake B.  Predictors of mortality in older patients following intensive care: the importance of functional status. J Am Geriatr Soc . 1991;;39:862-868.
Mundt DJ, Gage RW, Lemeshow S, Pastides H, Teres D, Avrunin JS.  Intensive care unit patient follow-up: mortality, functional status, and return to work at six months. Arch Intern Med . 1989;;149:68-72.
Wu AW, Rubin HR, Rosen MJ.  Are elderly people less responsive to intensive care? J Am Geriatr Soc . 1990;;38:621-627.
Pesau B, Falger S, Berger E, et al.  Influence of age on outcome of mechanically ventilated patients in an intensive care unit. Crit Care Med . 1992;;20:489-492.
Callahan D.  Old age and new policy. JAMA . 1989;;261:905-906.
Levinsky NG.  Age as a criterion for rationing health care. N Engl J Med . 1990;;322:1813-1816.
Katz S, Downs TD, Cash HR, Grotz RC.  Progress in development of the index of ADL. Gerontologist . (Spring) 1970;;pt 1:20-30.
Knaus WA, Draper EA, Wagner DP, Zimmerman JE.  APACHE II: a severity of disease classification system. Crit Care Med . 1985;;13:818-829.
Keene AR, Cullen DJ.  Therapeutic Intervention Scoring System: update 1983. Crit Care Med . 1983;;11:1-3.
Patrick DL, Danis M, Southerland LI, Hong G.  Quality of life following intensive care. J Gen Intern Med . 1988;;3:218-223.
Weissman MM, Sholomskas D, Pottenger M, Prusoff BA, Locke B.  Assessing depressive symptoms in five psychiatric populations: a validation study. Am J Epidemiol . 1977;;106:203-214.
Shrout PE, Yager TJ.  Reliability and validity of screening scales: effect of reducing scale length. J Clin Epidemiol . 1989;;42:69-78.
Danis M, Gerrity MS, Southerland LI, Patrick DL.  A comparison of patient, family and physician assessment of the value of medical intensive care. Crit Care Med . 1988;;16:594-600.
Thibault GE, Mulley AG, Barnett GO, et al.  Medical intensive care: indications, interventions and outcomes. N Engl J Med . 1980;;302:938-942.
Detsky AS, Stricker SC, Mulley AG, Thibault EG.  Prognosis, survival, and the expenditure of hospital resources for patients in an intensive care unit. N Engl J Med . 1981;;305:667-672.
Byrick RJ, Mindorff C, McKee L, Mudge B.  Cost-effectiveness of intensive care for respiratory failure patients. Crit Care Med . 1980;;8:332-337.
Slayter MA, James OF, Moore PG, Leeder SR.  Costs, severity of illness and outcome in intensive care. Anaesthesiol Intensive Care . 1986;;14:381-389.
Sage WM, Hurst CR, Silverman JF, Bortz WM.  Intensive care for the elderly: outcome of elective and nonelective admissions. J Am Geriatr Soc . 1987;; 35:312-318.
Oye RK, Bellamy PE.  Patterns of resource consumption in medical intensive care. Chest . 1991;;99: 685-689.
Riley SA.  Outcome prediction in intensive therapy. Intensive Crit Care Digest . 1991;;10:62-63.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Martin L.  Population aging policies in East Asia and the United States. Science . 1991;;251:527-532.
Rowe JW, Grossman E, Bond E.  Academic geriatrics for the year 2000: an institute of medicine report. N Engl J Med . 1987;;316:1425-1428.
Le Gall JR, Brun-Buisson C, Trunet P, Latournerie J, Chantereau S, Rapin M.  Influence of age, previous health status, and severity of acute illness on outcome from intensive care. Crit Care Med . 1982;;10:575-577.
Campion EW, Mulley AG, Goldstein RL, Barnett GO, Thibault E.  Medical intensive care for the elderly. JAMA . 1981;;246:2052-2056.
Cullen DJ, Keene R, Waternaux C, Kunsman JM, Caldera DL, Peterson H.  Results, charges and benefits of intensive care for critically ill patients: update 1983. Crit Care Med . 1984;;12:102-106.
Potgieter PD, Rosenthal E, Benatar SR.  Immediate and long-term survival in patients admitted to a respiratory ICU. Crit Care Med . 1985;;13:798-802.
McClish DK, Powell SH, Montenegro H, Nochomovitz M.  The impact of age on utilization of intensive care resources. J Am Geriatr Soc . 1987;;35: 983-988.
Mayer-Oakes SA, Oye RK, Leake B.  Predictors of mortality in older patients following intensive care: the importance of functional status. J Am Geriatr Soc . 1991;;39:862-868.
Mundt DJ, Gage RW, Lemeshow S, Pastides H, Teres D, Avrunin JS.  Intensive care unit patient follow-up: mortality, functional status, and return to work at six months. Arch Intern Med . 1989;;149:68-72.
Wu AW, Rubin HR, Rosen MJ.  Are elderly people less responsive to intensive care? J Am Geriatr Soc . 1990;;38:621-627.
Pesau B, Falger S, Berger E, et al.  Influence of age on outcome of mechanically ventilated patients in an intensive care unit. Crit Care Med . 1992;;20:489-492.
Callahan D.  Old age and new policy. JAMA . 1989;;261:905-906.
Levinsky NG.  Age as a criterion for rationing health care. N Engl J Med . 1990;;322:1813-1816.
Katz S, Downs TD, Cash HR, Grotz RC.  Progress in development of the index of ADL. Gerontologist . (Spring) 1970;;pt 1:20-30.
Knaus WA, Draper EA, Wagner DP, Zimmerman JE.  APACHE II: a severity of disease classification system. Crit Care Med . 1985;;13:818-829.
Keene AR, Cullen DJ.  Therapeutic Intervention Scoring System: update 1983. Crit Care Med . 1983;;11:1-3.
Patrick DL, Danis M, Southerland LI, Hong G.  Quality of life following intensive care. J Gen Intern Med . 1988;;3:218-223.
Weissman MM, Sholomskas D, Pottenger M, Prusoff BA, Locke B.  Assessing depressive symptoms in five psychiatric populations: a validation study. Am J Epidemiol . 1977;;106:203-214.
Shrout PE, Yager TJ.  Reliability and validity of screening scales: effect of reducing scale length. J Clin Epidemiol . 1989;;42:69-78.
Danis M, Gerrity MS, Southerland LI, Patrick DL.  A comparison of patient, family and physician assessment of the value of medical intensive care. Crit Care Med . 1988;;16:594-600.
Thibault GE, Mulley AG, Barnett GO, et al.  Medical intensive care: indications, interventions and outcomes. N Engl J Med . 1980;;302:938-942.
Detsky AS, Stricker SC, Mulley AG, Thibault EG.  Prognosis, survival, and the expenditure of hospital resources for patients in an intensive care unit. N Engl J Med . 1981;;305:667-672.
Byrick RJ, Mindorff C, McKee L, Mudge B.  Cost-effectiveness of intensive care for respiratory failure patients. Crit Care Med . 1980;;8:332-337.
Slayter MA, James OF, Moore PG, Leeder SR.  Costs, severity of illness and outcome in intensive care. Anaesthesiol Intensive Care . 1986;;14:381-389.
Sage WM, Hurst CR, Silverman JF, Bortz WM.  Intensive care for the elderly: outcome of elective and nonelective admissions. J Am Geriatr Soc . 1987;; 35:312-318.
Oye RK, Bellamy PE.  Patterns of resource consumption in medical intensive care. Chest . 1991;;99: 685-689.
Riley SA.  Outcome prediction in intensive therapy. Intensive Crit Care Digest . 1991;;10:62-63.
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