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ARTICLE |

What's in a Name When Efficacy Isn't Efficacious? FREE

Jack L. Lesher, Jr, MD
JAMA. 1992;268(24):3434-3434. doi:10.1001/jama.1992.03490240042029
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To the Editor.  —This letter relates to the article by Kreiss et al1 published in JAMA. I am concerned that the title is somewhat confusing, as it seems to suggest that the nonoxynol 9 may indeed be effective in preventing human immunodeficiency virus (HIV) acquisition. If I understand the article correctly, this is in fact not the case, and the authors state that they were unable to demonstrate that nonoxynol 9 sponge use was effective in reducing the risk of HIV infection among highly exposed women.I wonder if a title such as "Failure of Nonoxynol 9 Contraceptive Sponge Use..." or "Lack of Efficacy of Nonoxynol 9 Contraceptive Sponge Use..." would have been more appropriate. My fear is that busy clinicians may glance at a title and try to extract information from that, and in this case would come up with misleading information.I showed the title to my wife,

REFERENCES

Kreiss J, Ngugi E, Holmes K, et al.  Efficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes. JAMA . 1992;;268:477-482.

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Kreiss J, Ngugi E, Holmes K, et al.  Efficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes. JAMA . 1992;;268:477-482.
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