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Percutaneous Transluminal Coronary Angioplasty in New York State: Title and subTitle BreakRisk Factors and Outcomes FREE

Edward L. Hannan, PhD; Djavad T. Arani, MD; Lewis W. Johnson, MD; Harvey G. Kemp, Jr, MD; Gary Lukacik, MA
[+] Author Affiliations

Reprint requests to New York State Department of Health, 2019 Corning Tower Bldg, Albany, NY 12237 (Dr Hannan).


JAMA. 1992;268(21):3092-3097. doi:10.1001/jama.1992.03490210074038
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Objective.  —To identify significant independent risk factors for major percutaneous transluminal coronary angioplasty outcomes.

Design.  —Retrospective analysis using univariate and logistic regression analysis to identify significant independent risk factors for adverse outcomes.

Setting.  —All 31 hospitals performing percutaneous transluminal coronary angioplasty in New York State in 1991.

Patients.  —All 5827 patients undergoing percutaneous transluminal coronary angioplasty between January 1, 1991, and June 30, 1991, in New York State.

Main Outcome Measures.  —In-hospital mortality, major complication(s) (in-hospital mortality, myocardial infarction, and/or emergency coronary artery bypass graft), and absence of angiographic success (stenosis reduction of less than 20% on any attempted lesion or residual stenosis of at least 50% on any attempted lesion).

Main Results.  —Before discharge from the hospital, a total of 37 patients (0.63%) died; 67 patients (1.1%) suffered a myocardial infarction, with a mortality rate of 4.5%; and 97 patients (1.7%) underwent emergency coronary artery bypass graft surgery, with a mortality rate of 2.1% (no deaths in 85 patients who were hemodynamically stable and two deaths among 12 patients who were hemodynamically unstable). A total of 187 patients (3.2%) experienced a major complication. Angiographic success was achieved for 88% of all patients. Multivariate analysis found four independent preprocedural variables related to death: female gender, hemodynamic instability, shock, and ejection fraction.

Conclusions.  —Percutaneous transluminal coronary angioplasty outcomes in New York compare favorably with other recent results reported in the literature. Several preprocedural variables markedly increase the incidence of adverse events.(JAMA. 1992;268:3092-3097)

REFERENCES

Detre K, Holubkov R, Kelsey S, et al.  Percutaneous transluminal coronary angioplasty in 1985-1986 and 1977-1981: the National Heart, Lung, and Blood Registry. N Engl J Med . 1988;;318:265-270.
Holmes DJ, Holubkov R, Vlietstra R, et al.  Comparison of complications during percutaneous transluminal coronary angioplasty from 1977 to 1981 and from 1985 to 1986: the National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry. J Am Coll Cardiol . 1988;;12:1149-1155.
Ellis SG, Vandormael MG, Cowley MJ, et al.  Coronary morphologic and clinical determinants of procedural outcome for multivessel coronary disease: implications for patient selection. Circulation . 1990;;82:1193-1202.
Alfonso F, Macaya C, Iniguez A, Zarco P.  Repeat coronary angioplasty during the same angiographic diagnosis of coronary stenosis. Am Heart J . 1990;;119:237-241.
Finci L, Meier B, Steffinino G, Urban P, Melchior J-P, Rutishauser W.  Coronary angioplasty: results with expanded indications. Int J Cardiol . 1987;;15:165-175.
Glazier J, Varracchione T, Ryan T, Ruocco NA, Jacobs AK, Faxon DP.  Outcome in patients with recurrent stenosis after percutaneous transluminal balloon angioplasty. Br Heart J . 1989;;61:485-488.
Meier B, King SB III, Gruentzig A, et al.  Repeat coronary angioplasty. J Am Coll Cardiol . 1984;;4: 463-466.
Quigley PJ, Hlatky MA, Hinohara T, et al.  Repeat percutaneous transluminal coronary angioplasty and predictors of recurrent stenosis. Am J Cardiol . 1989;;63:409-413.
Savage MP, Goldberg S, Hirshfield S, et al.  Clinical and angiographic determinants of primary coronary angioplasty success. J Am Coll Cardiol . 1991;; 17:22-28.
Bredlau CE, Roubin GS, LeimgruberPP, Douglas JS, King SB III, Gruentzig AR.  In-hospital morbidity and mortality in patients undergoing elective coronary angioplasty. Circulation . 1985;;72:1044-1052.
Cook C, Hubner P.  Percutaneous transluminal coronary angioplasty in elderly patients: a comparison with younger patients. Age Ageing . 1989;;18: 219-222.
Dorros G, Lewin R, Mathiak L.  Percutaneous transluminal coronary angioplasty in multivessel coronary disease patients: short- and long-term follow-up in single and multiple dilatations. Clin Cardiol . 1988;;11:601-612.
Sahni R, Maniet A, Banka V.  Long-term efficacy of percutaneous transluminal angioplasty on incidence of myocardial infarction, relief of symptoms, and survival. Clin Cardiol . 1989;;12:427-431.
Shimizu Y, Tanaka T, Takayama Y, et al.  Clinical experience of percutaneous transluminal coronary angioplasty. Jpn Circ J . 1984;;48:457-464.
Simpfendorfer C, Knezinek V, Dorosti K, Franco I, Hollman J, Whitlew P.  A six-year evolution of percutaneous transluminal coronary angioplasty: the Cleveland Clinic experience, 1981-1986. Cleve Clin J Med . 1988;;55:299-302.
Steffenino G, Meier B, Finci L, et al.  Acute complications of elective coronary angioplasty: a review of 500 consecutive procedures. Br Heart J . 1988;;59:151-158.
Valentine P.  The role of coronary angioplasty in the management of ischemic heart disease. Med J Aust . 1987;;147:344-347.
Rapold H, David P, Guiteras VP, et al.  Restenosis and its determinants in first and repeat coronary angioplasty. Eur Heart J . 1987;;8:755-786.
Ellis SG, Roubin GS, King SB III, et al.  Inhospital cardiac mortality after acute closure after coronary angioplasty: analysis of risk factors from 8207 procedures. J Am Coll Cardiol . 1988;;11:211-216.
Raizner A, Hust R, Lewis J, Winters LW Jr, Batty JW, Roberts R.  Transluminal coronary angioplasty in the elderly. Am J Cardiol . 1986;;57:29-32.
Talley J, Hurst J, King SB III, et al.  Clinical outcome 5 years after attempted percutaneous transluminal coronary angioplasty in 427 patients. Circulation . 1988;;77:820-829.
 Subcommittee on Percutaneous Transluminal Angioplasty, American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures. Guidelines for Percutaneous Transluminal Coronary Angioplasty. J Am Coll Cardiol. 1988;;12:529-545.
Harrell F. The LOGIST procedure. In: SUGI Supplemental Library User's Guide . 5th ed. Cary, NC: SAS Institute Inc; 1986;:269-293.
Hosmer DW, Lemeshow S. Applied Logistic Regression . New York, NY: John Wiley & Sons Inc; 1989;.

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Detre K, Holubkov R, Kelsey S, et al.  Percutaneous transluminal coronary angioplasty in 1985-1986 and 1977-1981: the National Heart, Lung, and Blood Registry. N Engl J Med . 1988;;318:265-270.
Holmes DJ, Holubkov R, Vlietstra R, et al.  Comparison of complications during percutaneous transluminal coronary angioplasty from 1977 to 1981 and from 1985 to 1986: the National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry. J Am Coll Cardiol . 1988;;12:1149-1155.
Ellis SG, Vandormael MG, Cowley MJ, et al.  Coronary morphologic and clinical determinants of procedural outcome for multivessel coronary disease: implications for patient selection. Circulation . 1990;;82:1193-1202.
Alfonso F, Macaya C, Iniguez A, Zarco P.  Repeat coronary angioplasty during the same angiographic diagnosis of coronary stenosis. Am Heart J . 1990;;119:237-241.
Finci L, Meier B, Steffinino G, Urban P, Melchior J-P, Rutishauser W.  Coronary angioplasty: results with expanded indications. Int J Cardiol . 1987;;15:165-175.
Glazier J, Varracchione T, Ryan T, Ruocco NA, Jacobs AK, Faxon DP.  Outcome in patients with recurrent stenosis after percutaneous transluminal balloon angioplasty. Br Heart J . 1989;;61:485-488.
Meier B, King SB III, Gruentzig A, et al.  Repeat coronary angioplasty. J Am Coll Cardiol . 1984;;4: 463-466.
Quigley PJ, Hlatky MA, Hinohara T, et al.  Repeat percutaneous transluminal coronary angioplasty and predictors of recurrent stenosis. Am J Cardiol . 1989;;63:409-413.
Savage MP, Goldberg S, Hirshfield S, et al.  Clinical and angiographic determinants of primary coronary angioplasty success. J Am Coll Cardiol . 1991;; 17:22-28.
Bredlau CE, Roubin GS, LeimgruberPP, Douglas JS, King SB III, Gruentzig AR.  In-hospital morbidity and mortality in patients undergoing elective coronary angioplasty. Circulation . 1985;;72:1044-1052.
Cook C, Hubner P.  Percutaneous transluminal coronary angioplasty in elderly patients: a comparison with younger patients. Age Ageing . 1989;;18: 219-222.
Dorros G, Lewin R, Mathiak L.  Percutaneous transluminal coronary angioplasty in multivessel coronary disease patients: short- and long-term follow-up in single and multiple dilatations. Clin Cardiol . 1988;;11:601-612.
Sahni R, Maniet A, Banka V.  Long-term efficacy of percutaneous transluminal angioplasty on incidence of myocardial infarction, relief of symptoms, and survival. Clin Cardiol . 1989;;12:427-431.
Shimizu Y, Tanaka T, Takayama Y, et al.  Clinical experience of percutaneous transluminal coronary angioplasty. Jpn Circ J . 1984;;48:457-464.
Simpfendorfer C, Knezinek V, Dorosti K, Franco I, Hollman J, Whitlew P.  A six-year evolution of percutaneous transluminal coronary angioplasty: the Cleveland Clinic experience, 1981-1986. Cleve Clin J Med . 1988;;55:299-302.
Steffenino G, Meier B, Finci L, et al.  Acute complications of elective coronary angioplasty: a review of 500 consecutive procedures. Br Heart J . 1988;;59:151-158.
Valentine P.  The role of coronary angioplasty in the management of ischemic heart disease. Med J Aust . 1987;;147:344-347.
Rapold H, David P, Guiteras VP, et al.  Restenosis and its determinants in first and repeat coronary angioplasty. Eur Heart J . 1987;;8:755-786.
Ellis SG, Roubin GS, King SB III, et al.  Inhospital cardiac mortality after acute closure after coronary angioplasty: analysis of risk factors from 8207 procedures. J Am Coll Cardiol . 1988;;11:211-216.
Raizner A, Hust R, Lewis J, Winters LW Jr, Batty JW, Roberts R.  Transluminal coronary angioplasty in the elderly. Am J Cardiol . 1986;;57:29-32.
Talley J, Hurst J, King SB III, et al.  Clinical outcome 5 years after attempted percutaneous transluminal coronary angioplasty in 427 patients. Circulation . 1988;;77:820-829.
 Subcommittee on Percutaneous Transluminal Angioplasty, American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures. Guidelines for Percutaneous Transluminal Coronary Angioplasty. J Am Coll Cardiol. 1988;;12:529-545.
Harrell F. The LOGIST procedure. In: SUGI Supplemental Library User's Guide . 5th ed. Cary, NC: SAS Institute Inc; 1986;:269-293.
Hosmer DW, Lemeshow S. Applied Logistic Regression . New York, NY: John Wiley & Sons Inc; 1989;.
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