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Results of the Massachusetts Model Systems for Blood Cholesterol Screening Project FREE

Stephen Havas, MD, MPH, MS; Lauren Koumjian, MSc; Joel Reisman, MS; Lily Hsu, MS, RD; Susan Wozenski, MPH, JD
[+] Author Affiliations

Reprint requests to Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 655 W Baltimore St, Baltimore, MD 21201 (Dr Havas).


JAMA. 1991;266(3):375-381. doi:10.1001/jama.1991.03470030075027
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Objective.  —To evaluate the effectiveness of a model blood cholesterol screening program.

Design.  —Principal components included physician education, communitybased screenings, and follow-up. A lay or professional educator provided counseling and referral advice. Half of the subjects with high blood cholesterol levels received a reminder to see their physician.

Setting.  —135 sites in four Massachusetts communities.

Participants.  —10 428 adults. Males, the young, the poor, the less educated, and minorities were underrepresented.

Main Outcome Measures.  —Referral completion rates, blood cholesterol changes.

Results.  —51.5% of those referred had visited their physicians within 2 to 4 months, increasing to 65.6% within 6 to 12 months. Older age (odds ratio [OR], 1.17 per additional decade), more education (OR, 1.17 per additional level), higher blood cholesterol levels (OR, 1.19 per additional 0.51 mmol/L), previous knowledge of level (OR, 1.34), and receiving a reminder (OR, 1.24) were significantly associated with greater likelihood of referral completion, whereas the type of educator providing counseling was not. Physicians had remeasured the blood cholesterol level of 76% of those seen, given dietary counseling to 70%, and prescribed medication to 15%. Significant changes in dietary fat were reported by both compliers and noncompliers with advice to follow up with their physicians. Six months after screening, blood cholesterol levels were 3.6% lower in noncompliers, 4.4% lower in compliers not taking cholesterol-lowering medications, and 8.8% in compliers taking such medications.

Conclusions.  —An effective, community-based blood cholesterol screening program can attract diverse populations and can result in most participants with high levels following up with their physicians, making dietary changes, and lowering their cholesterol levels. Additional strategies may be needed to attract underrepresented groups and to reduce the apparent overuse of cholesterollowering medications.(JAMA. 1991;266:375-381)

REFERENCES

NIH Consensus Conference.  Lowering blood cholesterol to prevent heart disease. JAMA . 1985;;253:2080-2086.
 Report of the National Cholesterol Education Program's Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Arch Intern Med . 1988;;148:36-69.
Wynder L, Field F, Haley N.  Population screening for cholesterol determinations: a pilot study. JAMA . 1986;;256:2839-2842.
Greenland P, Levenkron J, Radley M, Baggs J, Manchester R, Bowley N.  Feasibility of large-scale cholesterol screening: experience with a portable capillary-blood testing device. Am J Public Health . 1987;;77:73-75.
Naughton MJ, Luepker RV, Strickland D.  The accuracy of portable cholesterol analyzers in public screening programs. JAMA . 1990;;263:1213-1217.
Havas S, Greenland P, Wones R, Schucker B.  Addressing unanswered questions about population cholesterol screenings: the Model Systems for Blood Cholesterol Screening Program. Am J Prev Med . 1989;;5:337-346.
National Cholesterol Education Program. Recommendations for Improving Cholesterol Measurement: A Report From the Laboratory Standardization Panel of the National Cholesterol Education Program . Washington, DC: US Public Health Service; 1990;. Publication NIH 90-2964.
US Dept of Agriculture Human Nutrition Information Service.  Dietary guidelines for Americans: avoid too much fat, saturated fat, and cholesterol. Home Garden Bull . (April) 1986;;232:1.
Block G, Dresser C, Hartman A, Carroll M.  Nutrient sources in the American diet: quantitative data from the NHANESII Survey, II: macronutrients and fats. Am J Epidemiol . 1985;;122:27-40.
Davis C.  The effect of regression to the mean in epidemiologic and clinical studies. Am J Epidemiol . 1976;;104:493-498.
National Diet-Heart Study Research Group. The National Diet-Heart Study Final Report . New York, NY: American Heart Association; 1968;. Monograph 18.
Rastam L, Luepker R, Pirie P.  Effect of screening and referral on follow-up and treatment of high blood cholesterol levels. Am J Prev Med . 1988;;4:244-248.
Wynder E, Harris R, Haley N.  Population screening for plasma cholesterol: community-based results from Connecticut. Am Heart J . 1989;;117:649-656.
Fischer P, Guinan K, Burke J, Karp W, Richards J.  Impact of a public cholesterol screening program. Arch Intern Med . 1990;;150:2567-2572.
Lefebvre C, Lasater T, Carleton R, Peterson G.  Theory and delivery of health programming in the community: the Pawtucket Heart Health Program. Prev Med . 1987;;16:80-95.
Rochella E, Ward G.  The National High Blood Pressure Education Program: a description of its utility as a generic program model. Health Educ Q . 1984;;11:225-242.
 Factors related to cholesterol screening and awareness—United States, 1989. MMWR . 1990;;39:633-637.
Prevention '89/'90: Federal Programs and Progress . Washington, DC: US Dept of Health and Human Services; 1990;:34.
Levy R.  Causes of the decline in cardiovascular mortality. Am J Cardiol . 1984;;54:7c-13c.
Garraway W, Whisnant J.  The changing pattern of hypertension and the declining incidence of stroke. JAMA . 1987;;258:214-217.
Kotchen J, McKean H, Jackson-Thayer S, Moore R, Straus R, Kotchen T.  Impact of a rural high blood pressure control program on hypertension control and cardiovascular disease mortality. JAMA . 1986;;255:2177-2182.

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NIH Consensus Conference.  Lowering blood cholesterol to prevent heart disease. JAMA . 1985;;253:2080-2086.
 Report of the National Cholesterol Education Program's Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Arch Intern Med . 1988;;148:36-69.
Wynder L, Field F, Haley N.  Population screening for cholesterol determinations: a pilot study. JAMA . 1986;;256:2839-2842.
Greenland P, Levenkron J, Radley M, Baggs J, Manchester R, Bowley N.  Feasibility of large-scale cholesterol screening: experience with a portable capillary-blood testing device. Am J Public Health . 1987;;77:73-75.
Naughton MJ, Luepker RV, Strickland D.  The accuracy of portable cholesterol analyzers in public screening programs. JAMA . 1990;;263:1213-1217.
Havas S, Greenland P, Wones R, Schucker B.  Addressing unanswered questions about population cholesterol screenings: the Model Systems for Blood Cholesterol Screening Program. Am J Prev Med . 1989;;5:337-346.
National Cholesterol Education Program. Recommendations for Improving Cholesterol Measurement: A Report From the Laboratory Standardization Panel of the National Cholesterol Education Program . Washington, DC: US Public Health Service; 1990;. Publication NIH 90-2964.
US Dept of Agriculture Human Nutrition Information Service.  Dietary guidelines for Americans: avoid too much fat, saturated fat, and cholesterol. Home Garden Bull . (April) 1986;;232:1.
Block G, Dresser C, Hartman A, Carroll M.  Nutrient sources in the American diet: quantitative data from the NHANESII Survey, II: macronutrients and fats. Am J Epidemiol . 1985;;122:27-40.
Davis C.  The effect of regression to the mean in epidemiologic and clinical studies. Am J Epidemiol . 1976;;104:493-498.
National Diet-Heart Study Research Group. The National Diet-Heart Study Final Report . New York, NY: American Heart Association; 1968;. Monograph 18.
Rastam L, Luepker R, Pirie P.  Effect of screening and referral on follow-up and treatment of high blood cholesterol levels. Am J Prev Med . 1988;;4:244-248.
Wynder E, Harris R, Haley N.  Population screening for plasma cholesterol: community-based results from Connecticut. Am Heart J . 1989;;117:649-656.
Fischer P, Guinan K, Burke J, Karp W, Richards J.  Impact of a public cholesterol screening program. Arch Intern Med . 1990;;150:2567-2572.
Lefebvre C, Lasater T, Carleton R, Peterson G.  Theory and delivery of health programming in the community: the Pawtucket Heart Health Program. Prev Med . 1987;;16:80-95.
Rochella E, Ward G.  The National High Blood Pressure Education Program: a description of its utility as a generic program model. Health Educ Q . 1984;;11:225-242.
 Factors related to cholesterol screening and awareness—United States, 1989. MMWR . 1990;;39:633-637.
Prevention '89/'90: Federal Programs and Progress . Washington, DC: US Dept of Health and Human Services; 1990;:34.
Levy R.  Causes of the decline in cardiovascular mortality. Am J Cardiol . 1984;;54:7c-13c.
Garraway W, Whisnant J.  The changing pattern of hypertension and the declining incidence of stroke. JAMA . 1987;;258:214-217.
Kotchen J, McKean H, Jackson-Thayer S, Moore R, Straus R, Kotchen T.  Impact of a rural high blood pressure control program on hypertension control and cardiovascular disease mortality. JAMA . 1986;;255:2177-2182.
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