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The Use of Autologous Blood: Title and subTitle BreakThe National Blood Resource Education Program Expert Panel FREE

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From the National Blood Resource Education Program, National Heart, Lung, and Blood Institute, Bethesda, Md.

Reprint requests to Coordinator, NBREP, National Heart, Lung, and Blood Institute, Bldg 31, Room 4A05, Bethesda, MD 20892 (Susan D. Rogus, RN, MS).


JAMA. 1990;263(3):414-417. doi:10.1001/jama.1990.03440030101029
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The risk of transmitting disease through blood transfusions continues to fall as additional blood donor screening and testing measures are implemented. Nevertheless, when a blood transfusion is needed during the perioperative period, autologous blood is the safest option for eligible patients. Three methods for obtaining autologous blood to use during or after a planned surgical procedure are preoperative autologous blood donation, perioperative blood salvage, and acute normovolemic hemodilution. These techniques can be used alone or in combination to decrease or eliminate a patient's exposure to homologous blood. However, because all transfusions carry some health risk and blood administration costs, autologous blood should not be collected or reinfused indiscriminately. Autologous blood services should be used for eligible patients who are likely to require a transfusion but should not be employed for minor procedures in which transfusion is unlikely.

(JAMA. 1990;263:414-417)

REFERENCES

Toy PTCY, Strauss RG, Stehling LC, et al.  Predeposited autologous blood for elective surgery. A national multicenter study . N Engl J Med. 1987;;316:517-520.
Kruskall MS, Leonard SS, Klapholz N.  Autologous blood donation during pregnancy: analysis of safety and blood use . Obstet Gynecol. 1987;;70:938-940.
Kruskall MS, Glazer EE, Leonard SS, et al.  Utilization and effectiveness of a hospital autologous preoperative blood donor program . Transfusion. 1986;;26:335-340.
Haugen RK, Hill GE.  A large-scale autologous blood program in a community hospital . JAMA. 1987;;257:1211-1214.
Love TR, Hendren WG, O'Keife DO, Daggett WM.  Transfusion of predonated autologous blood in elective cardiac surgery . Ann Thorac Surg. 1987;; 43:508-512.
Mann M, Sacks HJ, Goldfinger D.  Safety of autologous blood donation prior to elective surgery for a variety of potentially 'high risk' patients . Transfusion. 1983;;23:229-232.
Silvergleid AJ.  Safety and effectiveness of predeposit autologous transfusions in preteen and adolescent children . JAMA. 1987;;257:3403-3404.
McVay PA, Hoag RW, Hoag MS, Toy PTCY.  Safety and use of autologous blood donation during the third trimester of pregnancy . Am J Obstet Gynecol. 1989;;160:1479-1488.
Popovsky MA, Devine PA, Taswell HF.  Intraoperative autologous transfusion . Mayo Clin Proc. 1985;;60:125-134.
Johnson RG, Rosenkrantz KR, Preston RA, Hopkins C, Daggett WM.  The efficacy of postoperative autotransfusion in patients undergoing cardiac operations . Ann Thorac Surg. 1983;;36:173-179.
Thurer RL, Lytle BW, Cosgrove DM, Loop FD.  Autotransfusion following cardiac operations: a randomized, prospective study . Ann Thorac Surg. 1979;;27:500-507.
Cordell AR, Lavender SW.  An appraisal of blood salvage techniques in vascular and cardiac operations . Ann Thorac Surg. 1981;;31:421-425.
Hallett JW, Popovsky M, Ilstrup D.  Minimizing blood transfusions during abdominal aortic surgery: recent advances in rapid autotransfusion . J Vasc Surg. 1987;;5:601-606.
Lennon RL, Hosking MP, Gray JR, Klassen RA, Popovsky MA, Warner MA.  The effects of intraoperative blood salvage and induced hypotension on transfusion requirements during spinal surgical procedures . Mayo Clin Proc. 1987;;62:1090-1094.
Dzik WH, Jenkins R.  Use of intraoperative blood salvage during orthotopic liver transplantation . Arch Surg. 1985;;120:946-948.
Ansell J, Parrilla N, King M, et al.  Survival of autotransfused red blood cells recovered from the surgical field during cardiovascular operations . J Thorac Cardiovasc Surg. 1982;;84:387-391.
Reul GJ, Solis RT, Greenberg SD, Mattox KL, Whisennand HH.  Experience with autotransfusion in the surgical management of trauma . Surgery. 1974;;76:546-555.
DeRai P, Rebulla P.  Postsplenectomy blood salvage in anemic patients . JAMA. 1987;;258:1332.
Cohn LH, Fosberg AM, Anderson WP, Collins JJ.  The effects of phlebotomy, hemodilution, and autologous transfusion on systemic oxygenation and whole blood utilization in open heart surgery . Chest. 1975;;68:283-287.
Martin E, Hansen E, Peter K.  Acute limited normovolemic hemodilution: a method for avoiding homologous transfusion . World J Surg. 1987;;11:53-59.

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Toy PTCY, Strauss RG, Stehling LC, et al.  Predeposited autologous blood for elective surgery. A national multicenter study . N Engl J Med. 1987;;316:517-520.
Kruskall MS, Leonard SS, Klapholz N.  Autologous blood donation during pregnancy: analysis of safety and blood use . Obstet Gynecol. 1987;;70:938-940.
Kruskall MS, Glazer EE, Leonard SS, et al.  Utilization and effectiveness of a hospital autologous preoperative blood donor program . Transfusion. 1986;;26:335-340.
Haugen RK, Hill GE.  A large-scale autologous blood program in a community hospital . JAMA. 1987;;257:1211-1214.
Love TR, Hendren WG, O'Keife DO, Daggett WM.  Transfusion of predonated autologous blood in elective cardiac surgery . Ann Thorac Surg. 1987;; 43:508-512.
Mann M, Sacks HJ, Goldfinger D.  Safety of autologous blood donation prior to elective surgery for a variety of potentially 'high risk' patients . Transfusion. 1983;;23:229-232.
Silvergleid AJ.  Safety and effectiveness of predeposit autologous transfusions in preteen and adolescent children . JAMA. 1987;;257:3403-3404.
McVay PA, Hoag RW, Hoag MS, Toy PTCY.  Safety and use of autologous blood donation during the third trimester of pregnancy . Am J Obstet Gynecol. 1989;;160:1479-1488.
Popovsky MA, Devine PA, Taswell HF.  Intraoperative autologous transfusion . Mayo Clin Proc. 1985;;60:125-134.
Johnson RG, Rosenkrantz KR, Preston RA, Hopkins C, Daggett WM.  The efficacy of postoperative autotransfusion in patients undergoing cardiac operations . Ann Thorac Surg. 1983;;36:173-179.
Thurer RL, Lytle BW, Cosgrove DM, Loop FD.  Autotransfusion following cardiac operations: a randomized, prospective study . Ann Thorac Surg. 1979;;27:500-507.
Cordell AR, Lavender SW.  An appraisal of blood salvage techniques in vascular and cardiac operations . Ann Thorac Surg. 1981;;31:421-425.
Hallett JW, Popovsky M, Ilstrup D.  Minimizing blood transfusions during abdominal aortic surgery: recent advances in rapid autotransfusion . J Vasc Surg. 1987;;5:601-606.
Lennon RL, Hosking MP, Gray JR, Klassen RA, Popovsky MA, Warner MA.  The effects of intraoperative blood salvage and induced hypotension on transfusion requirements during spinal surgical procedures . Mayo Clin Proc. 1987;;62:1090-1094.
Dzik WH, Jenkins R.  Use of intraoperative blood salvage during orthotopic liver transplantation . Arch Surg. 1985;;120:946-948.
Ansell J, Parrilla N, King M, et al.  Survival of autotransfused red blood cells recovered from the surgical field during cardiovascular operations . J Thorac Cardiovasc Surg. 1982;;84:387-391.
Reul GJ, Solis RT, Greenberg SD, Mattox KL, Whisennand HH.  Experience with autotransfusion in the surgical management of trauma . Surgery. 1974;;76:546-555.
DeRai P, Rebulla P.  Postsplenectomy blood salvage in anemic patients . JAMA. 1987;;258:1332.
Cohn LH, Fosberg AM, Anderson WP, Collins JJ.  The effects of phlebotomy, hemodilution, and autologous transfusion on systemic oxygenation and whole blood utilization in open heart surgery . Chest. 1975;;68:283-287.
Martin E, Hansen E, Peter K.  Acute limited normovolemic hemodilution: a method for avoiding homologous transfusion . World J Surg. 1987;;11:53-59.
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