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ARTICLE |

Increased Fish Consumption May Be Risky FREE

Jeffery A. Foran, PhD; Barbara S. Glenn, MPH; Wendy Silverman
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Edited by Drummond Rennie, MD, Deputy Editor (West),


JAMA. 1989;262(1):28-28. doi:10.1001/jama.1989.03430010040012
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To the Editor.—  Several articles that discuss the benefits of consuming fish and fish oils have appeared in JAMA and other journals. Numerous epidemiologic studies and clinical trials have addressed the relationship between consumption of ω-J polyunsaturated fatty acids (ω-3 polyunsaturated fatty acids) derived from fish oils and the incidence of disease. Kromhout et al1 found an inverse relationship between fish consumption and 20-year mortality from coronary heart disease and suggest that ingesting as little as 30 g of fish per day (a single 1/2-lb fish meal per week) may be of value in preventing coronary heart disease. Further, ingestion of ω-J polyunsaturated fatty acids may be associated with decreased levels of plasma triglycerides, plasma cholesterol, low-density lipoprotein, and very-low— density lipoprotein.2 Fish oils also may play a role in the treatment of autoimmune and inflammatory disorders, psoriasis, and atopic dermatitis. However, there is conflicting information on the

REFERENCES

Kromhout D, Bosschieter EB, Coulander CD.  The inverse relation between fish consumption and 20-year mortality from heart disease . N Engl J Med. 1985;;312:1205-1209.
Herold PM, Kinsella JE.  Fish oil consumption and decreased risk of cardiovascular disease: a comparison of findings from animal and human feeding trials . Am J Clin Nutr. 1986;;43:566-598.
Yetiv JZ.  Clinical applications of fish oils . JAMA . 1988;;260:665-670.
Foran JA, Cox M, Croxton D.  Sport fish consumption advisories and projected cancer risks in the Great Lakes basin . Am J Public Health . 1989;;79:322-325.
Foran JA, VanderPloeg D.  Consumption advisories for sport fish in the Great Lakes basin . J Great Lakes Res. In press.

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Kromhout D, Bosschieter EB, Coulander CD.  The inverse relation between fish consumption and 20-year mortality from heart disease . N Engl J Med. 1985;;312:1205-1209.
Herold PM, Kinsella JE.  Fish oil consumption and decreased risk of cardiovascular disease: a comparison of findings from animal and human feeding trials . Am J Clin Nutr. 1986;;43:566-598.
Yetiv JZ.  Clinical applications of fish oils . JAMA . 1988;;260:665-670.
Foran JA, Cox M, Croxton D.  Sport fish consumption advisories and projected cancer risks in the Great Lakes basin . Am J Public Health . 1989;;79:322-325.
Foran JA, VanderPloeg D.  Consumption advisories for sport fish in the Great Lakes basin . J Great Lakes Res. In press.
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To understand the clinical management of acute heart failure syndromes.
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