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Mycosis Fungoides FREE

Daniel Tripodi, PhD
JAMA. 1989;261(13):1882-1882. doi:10.1001/jama.1989.03420130044018
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To the Editor.—  The report by Drs Weinstock and Horm1 of a significant increase in the incidence of mycosis fungoides over a study period from 1973 through 1984 is of considerable interest. As the authors point out, the etiology of this disease is obscure, but the recent observation of an association between infection by the human T-cell lymphotropic virus type V and disease2 is worth noting. These findings also support the view that a human T-cell lymphotropic virus may be a factor in the etiology.Edelson3 described the relationship between mycosis fungoides and the Sézary syndrome as variants of a T-cell-mediated disease—cutaneous T-cell lymphoma. While Drs Weinstock and Horm1 referred to the poor response to conventional therapy, a new form of therapy named photopheresis (the equipment for which is manufactured by Therakos) has been introduced for the treatment of cutaneous T-cell lymphoma. As originally reported by

REFERENCES

Weinstock MA, Horm JW.  Mycosis fungoides in the United States: increasing incidence and descriptive epidemiology . JAMA . 1988;;260:42-46.
Manzaro V, Gismondi A, Barilleri G, et al.  HTLV-V: a new human retrovirus isolated in a Tac-negative T-cell lymphoma/leukemia . Science . 1987;;238:1581-1583.
Edelson RL.  Cutaneous T-cell lymphoma: mycosis fungoides, Sezary syndrome and other variants . J Am Acad Dermatol. 1980;;2:89-106.
Edelson RL, Berger C, Gasparro F, et al.  Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy: preliminary results . N Engl J Med. 1987;; 316:297-303.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Weinstock MA, Horm JW.  Mycosis fungoides in the United States: increasing incidence and descriptive epidemiology . JAMA . 1988;;260:42-46.
Manzaro V, Gismondi A, Barilleri G, et al.  HTLV-V: a new human retrovirus isolated in a Tac-negative T-cell lymphoma/leukemia . Science . 1987;;238:1581-1583.
Edelson RL.  Cutaneous T-cell lymphoma: mycosis fungoides, Sezary syndrome and other variants . J Am Acad Dermatol. 1980;;2:89-106.
Edelson RL, Berger C, Gasparro F, et al.  Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy: preliminary results . N Engl J Med. 1987;; 316:297-303.
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