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Wide QRS Tachycardia in the Conscious Adult: Title and subTitle BreakVentricular Tachycardia Is the Most Frequent Cause FREE

Russell T. Steinman, MD; Cesar Herrera, MD; Claudio D. Schuger, MD; Michael H. Lehmann, MD
[+] Author Affiliations

Reprint requests to Division of Cardiology, Harper Hospital, 3990 John R St, Detroit, MI 48201 (Dr Steinman).


JAMA. 1989;261(7):1013-1016. doi:10.1001/jama.1989.03420070063031
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Hemodynamic stability during wide QRS tachycardia is commonly, albeit erroneously, taken as evidence for a supraventricular mechanism. To determine the magnitude for potential misdiagnosis in applying this notion clinically, we analyzed 20 consecutive cases of regular wide QRS tachycardia in conscious adult patients (mean age, 64 years). The most common heart disease was atherosclerotic (75%), with an associated history of remote myocardial infarction in 73% of the cases. Tachycardia was sustained for a mean of 4.8 hours prior to medical evaluation, with a mean rate of 186 beats per minute and mean systolic blood pressure of 111 mm Hg. A diagnosis of ventricular tachycardia (VT) was established in 17 cases (85%). In the patients with VT, atrioventricular dissociation was recognized on the 12-lead electrocardiogram in 38%, with Wellens' morphological features favoring the diagnosis in 73%. Following conversion to sinus rhythm, electrophysiological testing in 17 patients reproduced the clinical arrhythmia in 94% (with a replication rate of 100% in 15 patients with VT), with at least one additional unsuspected VT morphology induced in 53% of patients with VT. Thus, VT should be considered the most likely cause of regular wide QRS tachycardia in the conscious adult patient, especially with a history of remote myocardial infarction. Recognition of this simple principle and careful examination of the 12-lead electrocardiogram may help to prevent the misapplication of pharmacotherapy in the vast majority of these patients.

(JAMA 1989;261:1013-1016)

REFERENCES

Stewart RB, Bardy GH, Greene HL:  Wide complex tachycardia: Misdiagnosis and outcome after emergent therapy . Ann Intern Med 1986;;104:766-771.
Buxton AE, Marchlinski FE, Doherty JU, et al:  Hazards of intravenous verapamil for sustained ventricular tachycardia . Am J Cardiol 1987;;59: 1107-1110.
Morady F, Baerman JM, DiCarlo LA, et al:  A prevalent misconception regarding wide-complex tachycardias . JAMA 1985;;254:2790-2792.
Wellens HJJ, Bar FWHM, Lie KI:  The value of the electrocardiogram in the differential diagnosis of a tachycardia with a wide QRS complex . Am J Med 1978;;64:27-33.
Wellens HJJ:  The electrocardiogram 80 years after Einthoven . J Am Coll Cardiol 1986;;7:484-491.
Dongas J, Lehmann MH, Mahmud R, et al:  Value of preexisting bundle branch block in the electrocardiographic differentiation of supraventricular from ventricular origin of wide QRS tachycardia . Am J Cardiol 1985;;55:717-721.
Denker S, Lehmann M, Mahmud R, et al:  Facilitation of ventricular tachycardia induction with abrupt changes in ventricular cycle length . Am J Cardiol 1984;;53:508-515.
Josephson ME, Seides SF: Clinical Cardiac Electrophysiology: Techniques and Interpretations . Philadelphia, Lea & Febiger, 1979;, pp 247-251.
Akhtar M, Shenasa M, Jazaperi M, et al:  Wide QRS complex tachycardia: Reappraisal of a common clinical problem . Ann Intern Med , in press.
Bardy GH, Packer DL, German LD, et al:  Preexcited reciprocating tachycardia in patients with Wolff-Parkinson-White syndrome: Incidence and mechanisms . Circulation 1984;;70:377-391.
Graboys TB:  A practical approach to supraventricular tachycardia . Choices Cardiol 1987;;1:114-116.
Baerman JM, Morady F, DiCarlo LA, et al:  Differentiation of ventricular tachycardia from supraventricular tachycardia with aberration: Value of the clinical history . Ann Emerg Med 1987;;16:40-43.
Tchou P, Young P, Mahmud R, et al:  Useful clinical criteria for the diagnosis of ventricular tachycardia . Am J Med 1988;;84:53-56.
Saksena S, Ciccone JM, Craelius W, et al:  Studies on left ventricular function during sustained ventricular tachycardia . J Am Coll Cardiol 1984;;4:501-508.
Lima JA, Weiss JL, Guzman P, et al:  Incomplete filling and incoordinate contraction as mechanisms of hypotension during ventricular tachycardia in man . Circulation 1983;;68:928-938.
Braunwald E:  Symposium on cardiac arrhythmias: Introduction: With comments on the hemodynamic significance of atrial systole . Am J Med 1974;;37:665-669.
Hamer QWF, Rubin SA, Peter T, et al:  Factors that predict syncope during ventricular tachycardia in patients . Am Heart J 1984;;107:997-1005.
Wilber DJ, Davis MJ, Rosenbaum M, et al:  Incidence and determinants of multiple morphologically distinct sustained ventricular tachycardias . J Am Coll Cardiol 1987;;10:583-591.
Josephson ME, Horowitz LN, Farshidi A, et al:  Recurrent sustained ventricular tachycardia: IV. Pleomorphism . Circulation 1979;;59:459-468.
Miller JM, Kienzle MG, Harken AH, et al:  Morphologically distinct sustained ventricular tachycardias in coronary artery disease: Significance and surgical results . J Am Coll Cardiol 1984;;4:1073-1079.

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Stewart RB, Bardy GH, Greene HL:  Wide complex tachycardia: Misdiagnosis and outcome after emergent therapy . Ann Intern Med 1986;;104:766-771.
Buxton AE, Marchlinski FE, Doherty JU, et al:  Hazards of intravenous verapamil for sustained ventricular tachycardia . Am J Cardiol 1987;;59: 1107-1110.
Morady F, Baerman JM, DiCarlo LA, et al:  A prevalent misconception regarding wide-complex tachycardias . JAMA 1985;;254:2790-2792.
Wellens HJJ, Bar FWHM, Lie KI:  The value of the electrocardiogram in the differential diagnosis of a tachycardia with a wide QRS complex . Am J Med 1978;;64:27-33.
Wellens HJJ:  The electrocardiogram 80 years after Einthoven . J Am Coll Cardiol 1986;;7:484-491.
Dongas J, Lehmann MH, Mahmud R, et al:  Value of preexisting bundle branch block in the electrocardiographic differentiation of supraventricular from ventricular origin of wide QRS tachycardia . Am J Cardiol 1985;;55:717-721.
Denker S, Lehmann M, Mahmud R, et al:  Facilitation of ventricular tachycardia induction with abrupt changes in ventricular cycle length . Am J Cardiol 1984;;53:508-515.
Josephson ME, Seides SF: Clinical Cardiac Electrophysiology: Techniques and Interpretations . Philadelphia, Lea & Febiger, 1979;, pp 247-251.
Akhtar M, Shenasa M, Jazaperi M, et al:  Wide QRS complex tachycardia: Reappraisal of a common clinical problem . Ann Intern Med , in press.
Bardy GH, Packer DL, German LD, et al:  Preexcited reciprocating tachycardia in patients with Wolff-Parkinson-White syndrome: Incidence and mechanisms . Circulation 1984;;70:377-391.
Graboys TB:  A practical approach to supraventricular tachycardia . Choices Cardiol 1987;;1:114-116.
Baerman JM, Morady F, DiCarlo LA, et al:  Differentiation of ventricular tachycardia from supraventricular tachycardia with aberration: Value of the clinical history . Ann Emerg Med 1987;;16:40-43.
Tchou P, Young P, Mahmud R, et al:  Useful clinical criteria for the diagnosis of ventricular tachycardia . Am J Med 1988;;84:53-56.
Saksena S, Ciccone JM, Craelius W, et al:  Studies on left ventricular function during sustained ventricular tachycardia . J Am Coll Cardiol 1984;;4:501-508.
Lima JA, Weiss JL, Guzman P, et al:  Incomplete filling and incoordinate contraction as mechanisms of hypotension during ventricular tachycardia in man . Circulation 1983;;68:928-938.
Braunwald E:  Symposium on cardiac arrhythmias: Introduction: With comments on the hemodynamic significance of atrial systole . Am J Med 1974;;37:665-669.
Hamer QWF, Rubin SA, Peter T, et al:  Factors that predict syncope during ventricular tachycardia in patients . Am Heart J 1984;;107:997-1005.
Wilber DJ, Davis MJ, Rosenbaum M, et al:  Incidence and determinants of multiple morphologically distinct sustained ventricular tachycardias . J Am Coll Cardiol 1987;;10:583-591.
Josephson ME, Horowitz LN, Farshidi A, et al:  Recurrent sustained ventricular tachycardia: IV. Pleomorphism . Circulation 1979;;59:459-468.
Miller JM, Kienzle MG, Harken AH, et al:  Morphologically distinct sustained ventricular tachycardias in coronary artery disease: Significance and surgical results . J Am Coll Cardiol 1984;;4:1073-1079.
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