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ARTICLE |

Finding the High-Risk Patient With Coronary Artery Disease FREE

Hadyn T. Williams, MD
[+] Author Affiliations

Edited by Drummond Rennie, MD, Deputy Editor (West); Jody W. Zylke, MD, Contributing Editor; Sharon Iverson, Assistant Editor.


JAMA. 1988;260(5):635-635. doi:10.1001/jama.1988.03410050051012
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To the Editor.—  Dr Cheitlin1 deserves our thanks and commendations for his recent excellent review of risk stratification in patients with coronary artery disease. His proposed diagnostic algorithm is straightforward and appears very practical.However, certain aspects of Table 1 of his article, which compares the various techniques available for risk stratification, need further clarification. Positron-emitting isotopes are usually obtained from a cyclotron (charged-particle accelerator), not from a breeder reactor as stated in the table. Breeder reactors, which utilize fast neutrons to produce large amounts of electricity from uranium with high efficiency, have not been as widely used as the more familiar thermal or slow-neutron nuclear reactors. This is due to justified concerns over safety problems with the more unstable breeder reactors. Cyclotrons have been safely employed in the extensive production of radioisotopes for decades, and carry none of the meltdown risks of breeder reactors.Placing radionuclide wall motion

REFERENCES

Cheitlin MD:  Finding the high-risk patient with coronary artery disease . JAMA 1988;;259:2271-2277.
McPhee SJ, Garnick DW:  Imaging the heart: Cardiac scintigraphy and echocardiography in US hospitals (1983) . J Nucl Med 1986;;27:1635-1641.
Jacobson HG:  Application of positron emission tomography in the heart . JAMA 1988;;259:2438-2445.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Cheitlin MD:  Finding the high-risk patient with coronary artery disease . JAMA 1988;;259:2271-2277.
McPhee SJ, Garnick DW:  Imaging the heart: Cardiac scintigraphy and echocardiography in US hospitals (1983) . J Nucl Med 1986;;27:1635-1641.
Jacobson HG:  Application of positron emission tomography in the heart . JAMA 1988;;259:2438-2445.
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To understand the clinical management of acute heart failure syndromes.
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