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Anesthesia and Multiple Sclerosis FREE

David J. Birnbach, MD; Angela Bader, MD; Gerard W. Ostheimer, MD
JAMA. 1988;260(19):2838-2838. doi:10.1001/jama.1988.03410190086027
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To The Editor.—  We would like to respond to the article by Nelson et al1 entitled "Risk of Multiple Sclerosis Exacerbation During Pregnancy and Breast-feeding" in the June 17, 1988, issue of JAMA.An area of major concern to obstetric anesthesiologists is the potential for exacerbation of the symptoms of multiple sclerosis after delivery. Although a correlation between the use of regional anesthesia (epidural and spinal) for labor and delivery has been suggested, no study thus far has demonstrated conclusively the role that regional anesthesia may play in an exacerbation of the disease.In reviewing the records of all parturients with multiple sclerosis who received regional anesthesia for labor from 1982 through 1987, data at the Brigham and Women's Hospital, Boston, suggest that the choice of anesthetic may indeed affect the course of the disease.2 This remains a controversial area in the practice of anesthesiology, and, unfortunately, there

REFERENCES

Nelson LM, Frankin GM, Jones MC, et al:  Risk of multiple sclerosis exacerbation during pregnancy and breast-feeding . JAMA 1988;;259:3441-3443.
Bader AM, Hunt CO, Datta S, et al:  Anesthesia for the obstetric patient with multiple sclerosis . J Clin Anesth , in press.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Nelson LM, Frankin GM, Jones MC, et al:  Risk of multiple sclerosis exacerbation during pregnancy and breast-feeding . JAMA 1988;;259:3441-3443.
Bader AM, Hunt CO, Datta S, et al:  Anesthesia for the obstetric patient with multiple sclerosis . J Clin Anesth , in press.
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