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ARTICLE |

The Treatment of Vasculitis of the Central Nervous System FREE

Leonard H. Calabrese, DO; J. A. Mallek, MD
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Edited by Drummond Rennie, MD, Senior Contributing Editor; Sharon Iverson, Assistant Editor.


JAMA. 1987;258(6):778-778. doi:10.1001/jama.1987.03400060054012
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To the Editor.—  We read with interest the article by Stein et al1 on the use of cerebral angiography as a guide for therapy in isolated central nervous system vasculitis. We too have used this modality—for similar reasons—to follow up patients with vasculitis of the central nervous system and have been impressed with its utility.2 Unlike the situation reported by Stein et al, whose patient clearly had systemic lupus erythematosus apparently complicated by vasculitis of the central nervous system, we have performed follow-up cerebral angiography in two patients with primary angiitis of the central nervous system. This is a condition in which there is no evidence of systemic diseases that may be complicated by angiitis within the central nervous system, such as systemic necrotizing vasculitis, connective tissue disease, herpes zoster ophthalmicus, or lymphoma. We arbitrarily chose a six-month end point for angiographic follow-up and in two cases were

REFERENCES

Stein RL, Martino CR, Weinert DM, et al:  Cerebral angiography as a guide for therapy in isolated central nervous system vasculitis . JAMA 1987;;257:2193-2195.
Mallek JA, Calabrese LH:  Primary angiitis of the central nervous system (PACNS): A report of seven new cases and a proposal for diagnostic criteria , abstracted. Arthritis Rheum 1985;;28(suppl to No. (4) ):S16.

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Stein RL, Martino CR, Weinert DM, et al:  Cerebral angiography as a guide for therapy in isolated central nervous system vasculitis . JAMA 1987;;257:2193-2195.
Mallek JA, Calabrese LH:  Primary angiitis of the central nervous system (PACNS): A report of seven new cases and a proposal for diagnostic criteria , abstracted. Arthritis Rheum 1985;;28(suppl to No. (4) ):S16.
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