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ARTICLE |

Iron Deficiency Anemia: Have We Come Far Enough? FREE

James A. Stockman, III, MD
JAMA. 1987;258(12):1645-1647. doi:10.1001/jama.1987.03400120095033
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In the progress of medical science, a disease is recognized, its manifestations are elucidated, and treatments or preventive measures are instituted; we then hope that the problem might become one of historical interest. Sometimes, however, we fail to realize when the problem still exists, and by our therapeutic misadventures create new problems. As demonstrated by the article of Yip et al1 in this issue of The Journal, we indeed have come a long way in dealing with the problem of iron-deficiency anemia in childhood. When viewing the declining prevalence of anemia among low-income children in the United States, we should ask, however, if we have come far enough. To answer, it is useful to understand where we have been, where we are now, and in what directions we could be moving with respect to the prevention of iron deficiency.

Iron is among the most common and useful of all

REFERENCES

Yip R, Binkin NJ, Fleshood L, et al:  Declining prevalence of anemia among low-income children in the United States . JAMA 1987;;258:1619-1623.
Beutler E, Fairbanks VF, Fahey JL: Clinical Disorders of Iron Metabolism . New York, Grune & Stratton, 1963;, pp 1-18.
Latham RG: The Works of Thomas Sydenham, M.D. London, C & S Allard, 1850;, p 98.
Bland P:  Sur les maladies chlorotiques, et sur un mode de traitement specifique dans ces affections . Rev Med Franc Etrang 1832;;45:341.
Whipple GH, Robscheit FS, Hooper CW:  Blood regeneration following simple anemia: IV. Influence of meat, liver, and various extractives, alone or combined with standard diets . Am J Physiol 1920;;53:236.
Beard JL:  Iron fortification: Rationale and effects . Nutr Today 1986;;21:17.
Committee on Nutrition:  Iron supplementation for infants . Pediatrics 1976;;58:765.
Miller V, Sevaney S, Deinard A:  Impact of the WIC program on the iron status of infants . Pediatrics 1985;;75:100.
Vasquez-Seoane P, Windom R, Pearson HA:  Disappearance of iron deficiency anemia in a high-risk infant population given supplemental iron . N Engl J Med 1985;;313:1239.
Foman SJ:  Bioavailability of supplemental iron in commercially prepared dry infant cereals . J Pediatr 1987;;110:660.
Rees JM, Monsen ER, Merrill JE:  Iron fortification of infant foods . Clin Pediatr 1985;;24:707.
Dallman PR, Yip R, Johnson C:  Prevalence and causes of anemia in the United States, 1976 to 1980 . Am J Clin Nutr 1984;;39:437.
Oski FA, Honig AS:  The effects of therapy on the developmental scores of iron-deficient infants . J Pediatr 1978;;92:21.
Lozoff B, Brittenham GM, Viteri FE, et al:  The effects of short-term oral iron therapy on developmental deficits in iron-deficient anemic infants . J Pediatr 1982;;100:351.
Oski FA, Honig AS, Helu B, et al:  Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants . Pediatrics 1983;;71:877.
Lozoff B, Brittenham GM:  Behavioral aspects of iron deficiency . Prog Haematol 1985;;14:23.
Lozoff B, Brittenham GM, Wolf AW, et al:  Iron deficiency anemia and iron therapy effects on infant developmental test performance . Pediatrics 1987;;79: 981.
Crosby WH:  Yin, Yang and iron . Nutr Today 1986;;21:14.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Yip R, Binkin NJ, Fleshood L, et al:  Declining prevalence of anemia among low-income children in the United States . JAMA 1987;;258:1619-1623.
Beutler E, Fairbanks VF, Fahey JL: Clinical Disorders of Iron Metabolism . New York, Grune & Stratton, 1963;, pp 1-18.
Latham RG: The Works of Thomas Sydenham, M.D. London, C & S Allard, 1850;, p 98.
Bland P:  Sur les maladies chlorotiques, et sur un mode de traitement specifique dans ces affections . Rev Med Franc Etrang 1832;;45:341.
Whipple GH, Robscheit FS, Hooper CW:  Blood regeneration following simple anemia: IV. Influence of meat, liver, and various extractives, alone or combined with standard diets . Am J Physiol 1920;;53:236.
Beard JL:  Iron fortification: Rationale and effects . Nutr Today 1986;;21:17.
Committee on Nutrition:  Iron supplementation for infants . Pediatrics 1976;;58:765.
Miller V, Sevaney S, Deinard A:  Impact of the WIC program on the iron status of infants . Pediatrics 1985;;75:100.
Vasquez-Seoane P, Windom R, Pearson HA:  Disappearance of iron deficiency anemia in a high-risk infant population given supplemental iron . N Engl J Med 1985;;313:1239.
Foman SJ:  Bioavailability of supplemental iron in commercially prepared dry infant cereals . J Pediatr 1987;;110:660.
Rees JM, Monsen ER, Merrill JE:  Iron fortification of infant foods . Clin Pediatr 1985;;24:707.
Dallman PR, Yip R, Johnson C:  Prevalence and causes of anemia in the United States, 1976 to 1980 . Am J Clin Nutr 1984;;39:437.
Oski FA, Honig AS:  The effects of therapy on the developmental scores of iron-deficient infants . J Pediatr 1978;;92:21.
Lozoff B, Brittenham GM, Viteri FE, et al:  The effects of short-term oral iron therapy on developmental deficits in iron-deficient anemic infants . J Pediatr 1982;;100:351.
Oski FA, Honig AS, Helu B, et al:  Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants . Pediatrics 1983;;71:877.
Lozoff B, Brittenham GM:  Behavioral aspects of iron deficiency . Prog Haematol 1985;;14:23.
Lozoff B, Brittenham GM, Wolf AW, et al:  Iron deficiency anemia and iron therapy effects on infant developmental test performance . Pediatrics 1987;;79: 981.
Crosby WH:  Yin, Yang and iron . Nutr Today 1986;;21:14.
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