Cholesterol and Children FREE

Lewis A. Barness, MD

[+] Author Affiliations

Reprint requests to the Department of Pediatrics, University of South Florida College of Medicine, 12901 N 30th St, Tampa, FL 33612 (Dr Barness).

JAMA. 1986;256(20):2871-2871. doi:10.1001/jama.1986.03380200109031

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References

ABSTRACT

ABSTRACT | REFERENCES

THOUGH the epidemiologic relationship of elevated serum cholesterol levels to the development of arteriosclerosis is strong, the relationship of dietary cholesterol to serum cholesterol is less certain. Attempts at dietary restriction of cholesterol-containing foods alone are often accompanied by small or negligible decreases in serum cholesterol levels,¹ though restriction of intake of fat with cholesterol has been moderately successful in animals.² In those with defined errors in lipoprotein metabolism, in which the error is in intracellular transport of cholesterol, diet alone is also usually ineffective.^3,4

The pediatrician is faced with several problems simultaneously: the diet composition for the infant, child, and adolescent, the distribution of fats in the diet, the diagnosis and treatment of the child with a family history of early arteriosclerosis, and the recommendations of the American Heart Association (AHA).⁵

As for the diet of the infant, it seems reasonable to consider breast milk

REFERENCES

ABSTRACT | REFERENCES

Mauer AM: A pediatrician attends the National Institutes of Health Consensus Conference on lowering blood cholesterol . Pediatrics 1985;;76:125-126.

Wissler RW: Principle of the pathogenesis of arteriosclerosis , in Braunwald E (ed): Heart Disease: A Textbook of Cardiovascular Medicine , ed 2. Philadelphia, WB Saunders Co, 1984;, pp 1183-1204.

Brown MS, Goldstein JL: How LDL receptors influence cholesterol and atherosclerosis . Sci Am 1984;;251:58-66.

Hoeg JM, Gregg RE, Brewer HB: An approach to the management of hyperlipoproteinemia . JAMA 1986;;255:512-521.

Kwiterovich PO: Biochemical, clinical, epidemiologic, genetic and pathologic data in the pediatric age group relevant to the cholesterol hypothesis . Pediatrics 1986;;78:349-362.

Glueck CJ: Therapy of familial and acquired hyperlipoproteinemia in children and adolescents . Prev Med 1983;;12:835-841.

Carlson SE, Devoe P, Barness LA: Effect of infant diets with different polyunsaturated to saturated fat ratios on circulating high density lipoproteins . J Pediatr Gastroenterol Nutr 1982;;1:303-309.

Grundy SM: Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol . N Engl J Med 1986;;314:745-748.

Nestel PJ: Fish oil attenuates the cholesterol induced rise in lipoprotein cholesterol . Am J Clin Nutr 1986;;43:752-757.

Lands WEM: Renewed questions about polyunsaturated fatty acids . Nutr Rev 1986;;44:189-195.

Dyerberg J: Linolenate-derived polyunsaturated fatty acids and prevention of atherosclerosis . Nutr Rev 1986;;44:125-142.

Herold PM, Kinsilla JE: Fish oil consumption and decreased risk of cardiovascular disease . Am J Clin Nutr 1986;;43:566-598.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal